PDB entry 2wk4

View 2wk4 on RCSB PDB site
Description: Dimeric structure of D347G D348G mutant of the sapporovirus RNA dependent RNA polymerase
Class: hydrolase
Keywords: covalent protein-RNA linkage, nucleotidyltransferase, RNA replication, phosphorylation, RNA elongation, thiol protease, capsid protein, ATP-binding, helicase, protease, hydrolase
Deposited on 2009-06-05, released 2010-09-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.98 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protease-polymerase p70
    Species: SAPPORO VIRUS [TaxId:95342]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q69014
      • engineered mutation (346-347)
    Domains in SCOPe 2.08: d2wk4a_
  • Chain 'B':
    Compound: protease-polymerase p70
    Species: SAPPORO VIRUS [TaxId:95342]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q69014 (0-End)
      • engineered mutation (346-347)
    Domains in SCOPe 2.08: d2wk4b_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wk4A (A:)
defqwkglpvvksgldvggmptgtryhrspawpeeqpgethapapfgsgdkrytfsqtem
lvnglkpyteptagvppqllsravthvrsyietiigthrspvltyhqacellerttscgp
fvqglkgdywdeeqqqytgvlanhleqawdkankgiaprnayklalkdelrpieknkagk
rrllwgcdaattliataafkavatrlqvvtpmtpvavginmdsvqmqvmndslkggvlyc
ldyskwdstqnpavtaaslailerfaephpivscaiealsspaegyvndikfvtrgglps
gmpftsvvnsinhmiyvaaailqayeshnvpytgnvfqvetihtygggcmysvcpatasi
fhtvlanltsyglkptaadksdaikptntpvflkrtftqtphgirallditsitrqfywl
kanrtsdpssppafdrqarsaqlenalayasqhgpvmfdtvrqiaiktaqgeglvlvntn
ydqalatynawfiggtvpdpvghtegthkivfeme

    Sequence, based on observed residues (ATOM records): (download) 
    >2wk4A (A:)
qwkglpvvksgldvggmptgtryhrspawpeeqpgethapapfgsgdkrytfsqtemlvn
glkpyteptagvppqllsravthvrsyietiigthrspvltyhqacellerttscgpfvq
glkgdywdeeqqqytgvlanhleqawdkankgiaprnayklalkdelrpieknkagkrrl
lwgcdaattliataafkavatrlqvvtpmtpvavginmdsvqmqvmndslkggvlycldy
skwdstqnpavtaaslailerfaephpivscaiealsspaegyvndikfvtrgglpsgmp
ftsvvnsinhmiyvaaailqayeshnvpytgnvfqvetihtygggcmysvcpatasifht
vlanltsyglkptaadksdaikptntpvflkrtftqtphgirallditsitrqfywlkan
rtsdpssppafdrqarsaqlenalayasqhgpvmfdtvrqiaiktaqgeglvlvntnydq
alatynawfiggtvpdpvg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wk4B (B:)
defqwkglpvvksgldvggmptgtryhrspawpeeqpgethapapfgsgdkrytfsqtem
lvnglkpyteptagvppqllsravthvrsyietiigthrspvltyhqacellerttscgp
fvqglkgdywdeeqqqytgvlanhleqawdkankgiaprnayklalkdelrpieknkagk
rrllwgcdaattliataafkavatrlqvvtpmtpvavginmdsvqmqvmndslkggvlyc
ldyskwdstqnpavtaaslailerfaephpivscaiealsspaegyvndikfvtrgglps
gmpftsvvnsinhmiyvaaailqayeshnvpytgnvfqvetihtygggcmysvcpatasi
fhtvlanltsyglkptaadksdaikptntpvflkrtftqtphgirallditsitrqfywl
kanrtsdpssppafdrqarsaqlenalayasqhgpvmfdtvrqiaiktaqgeglvlvntn
ydqalatynawfiggtvpdpvghtegthkivfeme

    Sequence, based on observed residues (ATOM records): (download) 
    >2wk4B (B:)
defqwkglpvvksgldvggmptgtryhrspawpeeqpgethapapfgsgdkrytfsqtem
lvnglkpyteptagvppqllsravthvrsyietiigthrspvltyhqacellerttscgp
fvqglkgdywdeeqqqytgvlanhleqawdkankgiaprnayklalkdelrpieknkagk
rrllwgcdaattliataafkavatrlqvvtpmtpvavginmdsvqmqvmndslkggvlyc
ldyskwdstqnpavtaaslailerfaephpivscaiealsspaegyvndikfvtrgglps
gmpftsvvnsinhmiyvaaailqayeshnvpytgnvfqvetihtygggcmysvcpatasi
fhtvlanltsyglkptaadksdaikptntpvflkrtftqtphgirallditsitrqfywl
kanrtsdpssppafdrqarsaqlenalayasqhgpvmfdtvrqiaiktaqgeglvlvntn
ydqalatynawfiggtvpdpvg