PDB entry 2wge

View 2wge on RCSB PDB site
Description: Crystal structure of KasA of Mycobacterium tuberculosis with bound TLM
Class: transferase
Keywords: beta ketoacyl synthase I thiolactomycin, transferase, acyltransferase, lipid synthesis, fatty acid biosynthesis
Deposited on 2009-04-17, released 2009-07-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-04-11, with a file datestamp of 2012-04-06.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.16902
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase 1
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2wgea1, d2wgea2
  • Heterogens: GOL, IPA, TLM, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wgeA (A:)
msqpstanggfpsvvvtavtattsispdiestwkgllagesgihaledefvtkwdlavki
gghlkdpvdshmgrldmrrmsyvqrmgkllggqlwesagspevdpdrfavvvgtglggae
rivesydlmnaggprkvsplavqmimpngaaaviglqlgaragvmtpvsacssgseaiah
awrqivmgdadvavcggvegpiealpiaafsmmramstrndeperasrpfdkdrdgfvfg
eagalmlieteehakargakplarllgagitsdafhmvapaadgvragramtrslelagl
spadidhvnahgtatpigdaaeanairvagcdqaavyapksalghsigavgalesvltvl
tlrdgvipptlnyetpdpeidldvvageprygdyryavnnsfgfgghnvalafgry

    Sequence, based on observed residues (ATOM records): (download) 
    >2wgeA (A:)
sqpstanggfpsvvvtavtattsispdiestwkgllagesgihaledefvtkwdlavkig
ghlkdpvdshmgrldmrrmsyvqrmgkllggqlwesagspevdpdrfavvvgtglggaer
ivesydlmnaggprkvsplavqmimpngaaaviglqlgaragvmtpvsacssgseaiaha
wrqivmgdadvavcggvegpiealpiaafsmmramstrndeperasrpfdkdrdgfvfge
agalmlieteehakargakplarllgagitsdafhmvapaadgvragramtrslelagls
padidhvnahgtatpigdaaeanairvagcdqaavyapksalghsigavgalesvltvlt
lrdgvipptlnyetpdpeidldvvageprygdyryavnnsfgfgghnvalafgry