PDB entry 2wel

View 2wel on RCSB PDB site
Description: crystal structure of su6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin
Class: transferase
Keywords: cellular differentiation, serine/threonine-protein kinase, phosphoprotein, calmodulin-binding, calmodulin binding, kinase, transferase, ATP-binding, nucleotide-binding, vascular smooth muscle, serine-threonine kinase
Deposited on 2009-03-31, released 2009-04-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-08-10, with a file datestamp of 2011-08-05.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.1613
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calcium/calmodulin-dependent protein kinase type II delta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WEL (0-1)
    • Uniprot Q13557 (2-End)
    Domains in SCOPe 2.07: d2wela_
  • Chain 'D':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2weld_
  • Heterogens: K88, EDO, PO4, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2welA (A:)
    smtdeyqlfeelgkgafsvvrrcmkiptgqeyaakiintkklsardhqklerearicrll
    khpnivrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqilesvnhch
    lngivhrdlkpenlllaskskgaavkladfglaievqgdqqawfgfagtpgylspevlrk
    dpygkpvdmwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdl
    inkmltinpakritasealkhpwicqrstvasmmhrqetvdclkkfnarrklkgailttm
    latrnfsaaksllkkpdgvkestessn
    

    Sequence, based on observed residues (ATOM records): (download)
    >2welA (A:)
    smtdeyqlfeelgkgafsvvrrcmkiptgqeyaakiintkklsardhqklerearicrll
    khpnivrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqilesvnhch
    lngivhrdlkpenlllaskskgaavkladfglaievqgdqqawfgfagtpgylspevlrk
    dpygkpvdmwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdl
    inkmltinpakritasealkhpwicqrsmmhrqetvdclkkfnarrklkgailttmlatr
    nfsa
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2welD (D:)
    smadqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdad
    gngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltd
    eevdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >2welD (D:)
    dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
    tidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeev
    demireadidgdgqvnyeefvqmmt