PDB entry 2wbj

View 2wbj on RCSB PDB site
Description: TCR complex
Class: immune system
Keywords: transmembrane, immune response, t cell receptor, MHC II, membrane, receptor, molecular mimicry, multiple sclerosis, immune system, autoimmunity, glycoprotein, MHC class II
Deposited on 2009-03-02, released 2009-04-07
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-08-22, with a file datestamp of 2012-08-17.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.24909
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wbja1, d2wbja2
  • Chain 'B':
    Compound: hla class II histocompatibility antigen, drb1-15 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wbjb1, d2wbjb2
  • Chain 'C':
    Compound: ob tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WBJ (Start-199)
    Domains in SCOPe 2.04: d2wbjc1, d2wbjc2
  • Chain 'D':
    Compound: ob tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WBJ (0-End)
  • Chain 'E':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wbje1, d2wbje2
  • Chain 'F':
    Compound: hla class II histocompatibility antigen, drb1-15 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2wbjf1, d2wbjf2
  • Chain 'G':
    Compound: ob tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WBJ (Start-199)
    Domains in SCOPe 2.04: d2wbjg1, d2wbjg2
  • Chain 'H':
    Compound: ob tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WBJ
  • Heterogens: NAG, SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wbjA (A:)
ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
dapsplpettenvd

    Sequence, based on observed residues (ATOM records): (download) 
    >2wbjA (A:)
eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
iavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwl
rngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wbjB (B:)
gdtrprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaey
wnsqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvs
gfypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
tspltvewrarsesaqskvd

    Sequence, based on observed residues (ATOM records): (download) 
    >2wbjB (B:)
trprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaeywn
sqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqphhnllvcsvsgfyp
gsievrwflngqeekagmvstgliqngdwtfqtlvmletvpytcqvehpsvtspltvew

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2wbjC (C:)
mqqgeedpqalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgr
lrvtldtskksssllitasraadtasyfcatdttsgtykyifgtgtrlkvlpniqnpdpa
vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnk
sdfacanafnnsiipedtffpspendgggcklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2wbjC (C:)
pqalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgrlrvtldt
skksssllitasraadtasyfcatdttsgtykyifgtgtrlkvlpniqnpdpavyqlrds
kssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnksdfacan
afnnsiipedtff

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2wbjE (E:)
ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
dapsplpettenvd

    Sequence, based on observed residues (ATOM records): (download) 
    >2wbjE (E:)
ehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalani
avdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwlr
ngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2wbjF (F:)
gdtrprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaey
wnsqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvs
gfypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
tspltvewrarsesaqskvd

    Sequence, based on observed residues (ATOM records): (download) 
    >2wbjF (F:)
trprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaeywn
sqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvsgf
ypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsvts
pltvewra

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2wbjG (G:)
mqqgeedpqalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgr
lrvtldtskksssllitasraadtasyfcatdttsgtykyifgtgtrlkvlpniqnpdpa
vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnk
sdfacanafnnsiipedtffpspendgggcklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2wbjG (G:)
alsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgrlrvtldtsk
ksssllitasraadtasyfcatdttsgtykyifgtgtrlkvlpniqnpdpavyqlrssdk
svclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnksdfacanafnns
iipedtffps

  • Chain 'H':
    No sequence available.