PDB entry 2wbj

View 2wbj on RCSB PDB site
Description: TCR complex
Class: immune system
Keywords: transmembrane, immune response, t cell receptor, MHC II, membrane, receptor, molecular mimicry, multiple sclerosis, immune system, autoimmunity, glycoprotein, MHC class II
Deposited on 2009-03-02, released 2009-04-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-08-22, with a file datestamp of 2012-08-17.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.24909
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wbja1, d2wbja2
  • Chain 'B':
    Compound: hla class II histocompatibility antigen, drb1-15 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wbjb1, d2wbjb2
  • Chain 'C':
    Compound: ob tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WBJ (Start-199)
    Domains in SCOPe 2.07: d2wbjc1, d2wbjc2
  • Chain 'D':
    Compound: ob tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WBJ (0-End)
  • Chain 'E':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wbje1, d2wbje2
  • Chain 'F':
    Compound: hla class II histocompatibility antigen, drb1-15 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2wbjf1, d2wbjf2
  • Chain 'G':
    Compound: ob tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WBJ (Start-199)
    Domains in SCOPe 2.07: d2wbjg1, d2wbjg2
  • Chain 'H':
    Compound: ob tcr
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WBJ
  • Heterogens: NAG, SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2wbjA (A:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    dapsplpettenvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wbjA (A:)
    eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
    iavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwl
    rngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2wbjB (B:)
    gdtrprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaey
    wnsqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvs
    gfypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewrarsesaqskvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wbjB (B:)
    trprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaeywn
    sqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqphhnllvcsvsgfyp
    gsievrwflngqeekagmvstgliqngdwtfqtlvmletvpytcqvehpsvtspltvew
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2wbjC (C:)
    mqqgeedpqalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgr
    lrvtldtskksssllitasraadtasyfcatdttsgtykyifgtgtrlkvlpniqnpdpa
    vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnk
    sdfacanafnnsiipedtffpspendgggcklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wbjC (C:)
    pqalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgrlrvtldt
    skksssllitasraadtasyfcatdttsgtykyifgtgtrlkvlpniqnpdpavyqlrds
    kssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnksdfacan
    afnnsiipedtff
    

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >2wbjE (E:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    dapsplpettenvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wbjE (E:)
    ehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalani
    avdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwlr
    ngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >2wbjF (F:)
    gdtrprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaey
    wnsqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvs
    gfypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewrarsesaqskvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wbjF (F:)
    trprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaeywn
    sqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvsgf
    ypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsvts
    pltvewra
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >2wbjG (G:)
    mqqgeedpqalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgr
    lrvtldtskksssllitasraadtasyfcatdttsgtykyifgtgtrlkvlpniqnpdpa
    vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnk
    sdfacanafnnsiipedtffpspendgggcklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2wbjG (G:)
    alsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgrlrvtldtsk
    ksssllitasraadtasyfcatdttsgtykyifgtgtrlkvlpniqnpdpavyqlrssdk
    svclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnksdfacanafnns
    iipedtffps
    

  • Chain 'H':
    No sequence available.