PDB entry 2wa5

View 2wa5 on RCSB PDB site
Description: crystal structure of human filamin b actin binding domain at 1.9 angstroms resolution
Class: structural protein
Keywords: disease mutation, skeletal dysplasia, structural protein, actin-crosslinking, myogenesis, cytoskeleton, actin-binding, calponin homology domain, phosphoprotein, differentiation, atelosteogenesis, mutant, filamin, dwarfism, ch domain, developmental protein
Deposited on 2009-02-03, released 2009-06-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-06-02.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.192
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Filamin-B
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WA5 (Start-3)
    • Uniprot O75369 (4-244)
    Domains in SCOPe 2.08: d2wa5a1, d2wa5a2, d2wa5a3
  • Heterogens: SO4, CO3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wa5A (A:)
gamapvtekdlaedapwkkiqqntftrwcnehlkcvnkrignlqtdlsdglrliallevl
sqkrmyrkyhqrptfrqmqlenvsvalefldresiklvsidskaivdgnlklilglvwtl
ilhysismpvwedegdddakkqtpkqrllgwiqnkipylpitnfnqnwqdgkalgalvds
capglcpdweswdpqkpvdnareamqqaddwlgvpqvitpeeiihpdvdehsvmtylsqf
pkakl

    Sequence, based on observed residues (ATOM records): (download) 
    >2wa5A (A:)
mapvtekdlaedapwkkiqqntftrwcnehlkcvnkrignlqtdlsdglrliallevlsq
krmyrkyhqrptfrqmqlenvsvalefldresiklvsidskaivdgnlklilglvwtlil
hysismpvwedekqtpkqrllgwiqnkipylpitnfnqnwqdgkalgalvdscapglcpd
weswdpqkpvdnareamqqaddwlgvpqvitpeeiihpdvdehsvmtylsqfpkakl