PDB entry 2w17

View 2w17 on RCSB PDB site
Description: cdk2 in complex with the imidazole pyrimidine amide, compound (s)-8b
Class: transferase
Keywords: kinase, mitosis, cell cycle, transferase, serine/threonine-protein kinase, ATP-binding, cell division, phosphoprotein, phosphorylation, nucleotide-binding
Deposited on 2008-10-15, released 2008-11-04
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-06-02.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.244
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W17
    • Uniprot P24941 (0-297)
    Domains in SCOPe 2.01: d2w17a_
  • Heterogens: ACT, I19, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w17A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2w17A (A:)
menfqkvekigetygvvykarnkltgevvalkkirldvpstaireisllkelnhpnivkl
ldvihteklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
lkpqnllintegaikladfglavvtlwyrapeillgckyystavdiwslgcifaemvtrr
alfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgr
sllsqmlhydpnkrisakaalahpffqdvtkpvphlrl