PDB entry 2w06

View 2w06 on RCSB PDB site
Description: structure of cdk2 in complex with an imidazolyl pyrimidine, compound 5c
Class: transferase
Keywords: kinase, mitosis, cell cycle, transferase, serine/threonine-protein kinase, ATP-binding, polymorphism, cell division, phosphoprotein, phosphorylation, nucleotide-binding
Deposited on 2008-08-08, released 2008-09-23
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: 0.2052
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W06
    • Uniprot P24941 (0-297)
    Domains in SCOPe 2.04: d2w06a_
  • Heterogens: FRV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w06A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2w06A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirvpstaireisllkelnhpnivkll
dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
lkpqnllintegaikladfglarafevvtlwyrapeillgckyystavdiwslgcifaem
vtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppld
edgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl