PDB entry 2vxv

View 2vxv on RCSB PDB site
Description: Crystal structure of human IgG ABT-325 Fab Fragment
Class: immune system
Keywords: immune system, il-18, fab, th1/th2 cells, autoimmunity
Deposited on 2008-07-10, released 2009-06-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-03, with a file datestamp of 2019-03-29.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: human igg abt-325
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VXV (0-End)
    Domains in SCOPe 2.08: d2vxvh_
  • Chain 'L':
    Compound: human igg abt-325
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VXV (0-213)
    Domains in SCOPe 2.08: d2vxvl1, d2vxvl2
  • Heterogens: CXS, GOL, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2vxvH (H:)
evqlvqsgtevkkpgeslkisckgsgytvtsywigwvrqmpgkglewmgfiypgdsetry
sptfqgqvtisadksfntaflqwsslkasdtamyycarvgsgwypytfdiwgqgtmvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks

    Sequence, based on observed residues (ATOM records): (download) 
    >2vxvH (H:)
evqlvqsgtevkkpgeslkisckgsgytvtsywigwvrqmpgkglewmgfiypgdsetry
sptfqgqvtisadksfntaflqwsslkasdtamyycarvgsgwypytfdiwgqgtmvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2vxvL (L:)
eivmtqspatlsvspgeratlscrasesissnlawyqqkpgqaprlfiytastratdipa
rfsgsgsgteftltisslqsedfavyycqqynnwpsitfgqgtrleikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrge