PDB entry 2vv3

View 2vv3 on RCSB PDB site
Description: hPPARgamma Ligand binding domain in complex with 4-oxoDHA
Class: receptor
Keywords: nuclear receptor, transcription regulation, ligand binding domain, diabetes mellitus, zinc-finger, DNA-binding, transcription, obesity, nucleus, receptor, activator, oxidised fatty acid, transcription factor, metal-binding, phosphoprotein, disease mutation
Deposited on 2008-06-02, released 2008-08-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-06-06, with a file datestamp of 2012-06-01.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: 0.225
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2vv3a_
  • Chain 'B':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2vv3b_
  • Heterogens: 4R8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vv3A (A:)
galnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
ikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkyg
vheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldd
sdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtd
lrqivtehvqllqvikktetdmslhpllqeiykdly

    Sequence, based on observed residues (ATOM records): (download) 
    >2vv3A (A:)
esadlralakhlydsyiksfpltkakarailtgktdkspfviydmnslmmgedkikkeva
irifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdg
vlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrp
gllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikk
tetdmslhpllqeiykd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vv3B (B:)
galnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
ikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkyg
vheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldd
sdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtd
lrqivtehvqllqvikktetdmslhpllqeiykdly

    Sequence, based on observed residues (ATOM records): (download) 
    >2vv3B (B:)
esadlralakhlydsyiksfpltkakarailtgkdkspfviydmnslmmgedkievairi
fqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvli
segqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgll
nvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktpl
lqeiyk