PDB entry 2vu9

View 2vu9 on RCSB PDB site
Description: crystal structure of botulinum neurotoxin serotype a binding domain in complex with gt1b
Class: hydrolase
Keywords: hydrolase, metalloprotease, neurotoxin, ganglioside, metal-binding, toxin, protease, membrane, receptor, secreted
Deposited on 2008-05-22, released 2008-08-26
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.162
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: botulinum neurotoxin a heavy chain
    Species: CLOSTRIDIUM BOTULINUM [TaxId:36826]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VU9 (443-443)
    • Uniprot P10845 (22-442)
    Domains in SCOPe 2.03: d2vu9a1, d2vu9a2
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vu9A (A:)
mgsshhhhhhssglvprgshmdtsilnlryesnhlidlsryaskinigskvnfdpidknq
iqlfnlesskievilknaivynsmyenfstsfwiripkyfnsislnneytiincmennsg
wkvslnygeiiwtlqdtqeikqrvvfkysqminisdyinrwifvtitnnrlnnskiying
rlidqkpisnlgnihasnnimfkldgcrdthryiwikyfnlfdkelnekeikdlydnqsn
sgilkdfwgdylqydkpyymlnlydpnkyvdvnnvgirgymylkgprgsvmttniylnss
lyrgtkfiikkyasgnkdnivrnndrvyinvvvknkeyrlatnasqagvekilsaleipd
vgnlsqvvvmkskndqgitnkckmnlqdnngndigfigfhqfnniaklvasnwynrqier
ssrtlgcswefipvddgwgerplq

    Sequence, based on observed residues (ATOM records): (download) 
    >2vu9A (A:)
hmdtsilnlryesnhlidlsryaskinigskvnfdpidknqiqlfnlesskievilknai
vynsmyenfstsfwiripkyfnsislnneytiincmennsgwkvslnygeiiwtlqdtqe
ikqrvvfkysqminisdyinrwifvtitnnrlnnskiyingrlidqkpisnlgnihasnn
imfkldgcrdthryiwikyfnlfdkelnekeikdlydnqsnsgilkdfwgdylqydkpyy
mlnlydpnkyvdvnnvgirgymylkgprgsvmttniylnsslyrgtkfiikkyasgnkdn
ivrnndrvyinvvvknkeyrlatnasqagvekilsaleipdvgnlsqvvvmkskndqgit
nkckmnlqdnngndigfigfhqfnniaklvasnwynrqierssrtlgcswefipvddgwg
erplq