PDB entry 2vtz

View 2vtz on RCSB PDB site
Description: Biosynthetic thiolase from Z. ramigera. Complex of the C89A mutant with coenzyme A.
Class: transferase
Keywords: acyltransferase, phb biosynthesis, thiolase fold, transferase
Deposited on 2008-05-19, released 2008-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • engineered mutation (88)
      • conflict (128)
    • PDB 2VTZ (10-10)
    Domains in SCOPe 2.08: d2vtza1, d2vtza2
  • Chain 'B':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • engineered mutation (88)
      • conflict (128)
    • PDB 2VTZ (10-10)
    Domains in SCOPe 2.08: d2vtzb1, d2vtzb2
  • Chain 'C':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • engineered mutation (88)
      • conflict (128)
    • PDB 2VTZ (10-10)
    Domains in SCOPe 2.08: d2vtzc1, d2vtzc2
  • Chain 'D':
    Compound: Acetyl-CoA acetyltransferase
    Species: ZOOGLOEA RAMIGERA [TaxId:350]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07097 (11-391)
      • engineered mutation (88)
      • conflict (128)
    • PDB 2VTZ (10-10)
    Domains in SCOPe 2.08: d2vtzd1, d2vtzd2
  • Heterogens: COA, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vtzA (A:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlagsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaighpigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2vtzA (A:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlagsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaighpigasgarilntllf
emkrrgarkglatlcigggmgvamciesl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vtzB (B:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlagsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaighpigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2vtzB (B:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlagsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaighpigasgarilntllf
emkrrgarkglatlcigggmgvamciesl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2vtzC (C:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlagsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaighpigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2vtzC (C:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlagsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaighpigasgarilntllf
emkrrgarkglatlcigggmgvamciesl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vtzD (D:)
stpsiviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpa
gegqnparqaamkagvpqeatawgmnqlagsglravalgmqqiatgdasiivaggmesms
maphcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafav
asqnkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegt
vtagnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkal
eragwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaighpigasgarilnt
llfemkrrgarkglatlcigggmgvamciesl

    Sequence, based on observed residues (ATOM records): (download) 
    >2vtzD (D:)
siviasaartavgsfngafantpahelgatvisavleragvaagevnevilgqvlpageg
qnparqaamkagvpqeatawgmnqlagsglravalgmqqiatgdasiivaggmesmsmap
hcahlrggvkmgdfkmidtmikdgltdafygyhmgttaenvakqwqlsrdeqdafavasq
nkaeaaqkdgrfkdeivpfivkgrkgditvdadeyirhgatldsmaklrpafdkegtvta
gnasglndgaaaallmseaeasrrgiqplgrivswatvgvdpkvmgtgpipasrkalera
gwkigdldlveaneafaaqacavnkdlgwdpsivnvnggaiaighpigasgarilntllf
emkrrgarkglatlcigggmgvamciesl