PDB entry 2vrw
View 2vrw on RCSB PDB site
Description: critical structural role for the ph and c1 domains of the vav1 exchange factor
Class: signaling protein
Keywords: lipoprotein, GTP-binding, metal-binding, proto-oncogene, phosphoprotein, exchange factor, rac, vav, gtpase, membrane, sh2 domain, sh3 domain, methylation, zinc-finger, prenylation, guanine-nucleotide releasing factor, phorbol-ester binding, ADP-ribosylation, nucleotide-binding, signaling protein
Deposited on
2008-04-16, released
2008-06-17
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-31.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.205
AEROSPACI score: 0.48
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: ras-related c3 botulinum toxin substrate 1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2vrwa_ - Chain 'B':
Compound: Proto-oncogene vav
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Heterogens: ZN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2vrwA (A:)
mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcpp
pvkk
Sequence, based on observed residues (ATOM records): (download)
>2vrwA (A:)
mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl
- Chain 'B':
No sequence available.