PDB entry 2vrw

View 2vrw on RCSB PDB site
Description: critical structural role for the ph and c1 domains of the vav1 exchange factor
Class: signaling protein
Keywords: lipoprotein, GTP-binding, metal-binding, proto-oncogene, phosphoprotein, exchange factor, rac, vav, gtpase, membrane, sh2 domain, sh3 domain, methylation, zinc-finger, prenylation, guanine-nucleotide releasing factor, phorbol-ester binding, ADP-ribosylation, nucleotide-binding, signaling protein
Deposited on 2008-04-16, released 2008-06-17
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.205
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ras-related c3 botulinum toxin substrate 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2vrwa_
  • Chain 'B':
    Compound: Proto-oncogene vav
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2vrwA (A:)
    mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
    qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
    ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcpp
    pvkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2vrwA (A:)
    mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
    qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
    ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl
    

  • Chain 'B':
    No sequence available.