PDB entry 2v8x

View 2v8x on RCSB PDB site
Description: crystallographic and mass spectrometric characterisation of eif4e with n7-cap derivatives
Class: translation
Keywords: translation, phosphorylation, initiation factor, cap, eif4e, 7bngmp, 4e-bp1, RNA-binding, acetylation, host-virus interaction, protein synthesis inhibitor, protein biosynthesis, translation regulation
Deposited on 2007-08-16, released 2007-08-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.192
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: eukaryotic translation initiation factor 4e
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2v8xa1
  • Chain 'B':
    Compound: eukaryotic translation initiation factor 4e-binding protein 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: eukaryotic translation initiation factor 4e
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2v8xe1
  • Chain 'F':
    Compound: eukaryotic translation initiation factor 4e-binding protein 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MGQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2v8xA (A:)
matvepettptpnpptteeektesnqevanpehyikhplqnrwalwffkndksktwqanl
rliskfdtvedfwalynhiqlssnlmpgcdyslfkdgiepmwedeknkrggrwlitlnkq
qrrsdldrfwletllcligesfddysddvcgavvnvrakgdkiaiwttecenreavthig
rvykerlglppkivigyqshadtatksgsttknrfvv

    Sequence, based on observed residues (ATOM records): (download) 
    >2v8xA (A:)
ehyikhplqnrwalwffkndksktwqanlrliskfdtvedfwalynhiqlssnlmpgcdy
slfkdgiepmwedeknkrggrwlitlnkqqrrsdldrfwletllcligesfddysddvcg
avvnvrakgdkiaiwttecenreavthigrvykerlglppkivigyqshadtattknrfv
v

  • Chain 'B':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2v8xE (E:)
matvepettptpnpptteeektesnqevanpehyikhplqnrwalwffkndksktwqanl
rliskfdtvedfwalynhiqlssnlmpgcdyslfkdgiepmwedeknkrggrwlitlnkq
qrrsdldrfwletllcligesfddysddvcgavvnvrakgdkiaiwttecenreavthig
rvykerlglppkivigyqshadtatksgsttknrfvv

    Sequence, based on observed residues (ATOM records): (download) 
    >2v8xE (E:)
yikhplqnrwalwffkndksktwqanlrliskfdtvedfwalynhiqlssnlmpgcdysl
fkdgiepmwedeknkrggrwlitlnkqqrrsdldrfwletllcligesfddysddvcgav
vnvrakgdkiaiwttecenreavthigrvykerlglppkivigyqshadtsttknrfvv

  • Chain 'F':
    No sequence available.