PDB entry 2v2x
View 2v2x on RCSB PDB site
Description: t cell cross-reactivity and conformational changes during tcr engagement.
Class: immune system
Keywords: immune system, transmembrane, ubl conjugation, immune response, disease mutation, MHC tcr hla-a2 hiv, immunoglobulin domain, host-virus interaction, MHC I, membrane, polymorphism, glycoprotein, pyrrolidone carboxylic acid
Deposited on
2007-06-07, released
2007-11-06
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.194
AEROSPACI score: 0.58
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2v2xa1, d2v2xa2 - Chain 'B':
Compound: beta-2 microglobulin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 2V2X (1-9)
- Uniprot P61769 (1-99)
Domains in SCOPe 2.06: d2v2xb2, d2v2xb3 - Chain 'C':
Compound: hiv p17
Species: HUMAN IMMUNODEFICIENCY VIRUS, synthetic [TaxId:12721]
- Chain 'D':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2v2xd1, d2v2xd2 - Chain 'E':
Compound: beta-2 microglobulin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 2V2X (1-9)
- Uniprot P61769 (1-99)
Domains in SCOPe 2.06: d2v2xe2, d2v2xe3 - Chain 'F':
Compound: hiv p17
Species: HUMAN IMMUNODEFICIENCY VIRUS, synthetic [TaxId:12721]
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2v2xA (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwep
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2v2xB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>2v2xD (D:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwep
- Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)
>2v2xE (E:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'F':
No sequence available.