PDB entry 2v0d

View 2v0d on RCSB PDB site
Description: crystal structure of human cdk2 complexed with a thiazolidinone inhibitor
Class: transferase
Keywords: phosphorylation, nucleotide-binding, serine/threonine-protein kinase, transferase, ATP-binding, cell division, nucleotide- binding, thiazolidinone ligand, cdk2, kinase, cyclin, mitosis, cell cycle
Deposited on 2007-05-14, released 2007-06-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.197
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2v0da_
  • Heterogens: C53, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2v0dA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2v0dA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirlvpstaireisllkelnhpnivkl
    ldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhr
    dlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdi
    wslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarq
    dfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl