PDB entry 2uvu

View 2uvu on RCSB PDB site
Description: crystal structures of mutant dpo4 DNA polymerases with 8-oxog containing DNA template-primer constructs
Class: transferase
Keywords: DNA-directed DNA polymerase, p2 DNA polymerase IV, nucleotidyltransferase, 7, magnesium, DNA damage, DNA repair, DNA-binding, translesion DNA polymerase, transferase, DNA- binding, metal-binding, 8-dihydro-8-oxodeoxyguanosine, metal- binding, mutator protein, DNA replication
Deposited on 2007-03-14, released 2007-05-08
The last revision prior to the SCOP 1.75 freeze date was dated 2007-07-10, with a file datestamp of 2007-07-06.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.216
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase IV
    Species: SULFOLOBUS SOLFATARICUS
    Database cross-references and differences (RAF-indexed):
    • PDB 2UVU (6-23)
      • engineered mutation (337)
    • Uniprot Q97W02 (6-End)
    Domains in SCOP 1.75: d2uvua1, d2uvua2
  • Chain 'P':
    Compound: 5'-d(*gp*gp*gp*gp*gp*ap*ap*gp*gp*ap *tp*tp*cp*a)-3'
  • Chain 'T':
    Compound: 5'-d(*tp*cp*ap*cp*8ogp*gp*ap*ap*tp*cp *cp*tp*tp*cp*cp*cp*cp*c)-3'
  • Heterogens: CA, DGT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2uvuA (A:)
hhhhhhmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfg
vkagipiveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdk
vrdyreaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrl
ireldiadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeyn
epirtrvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedld
ivsrgrtfphgisketaysesvkllqkileederkiraigvrfskfieaigldkffdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2uvuA (A:)
hmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfgvkagi
piveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdkvrdyr
eaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrlireld
iadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeynepirt
rvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedldivsrg
rtfphgisketaysesvkllqkileederkiraigvrfskfiea

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.