PDB entry 2tod

View 2tod on RCSB PDB site
Description: ornithine decarboxylase from trypanosoma brucei k69a mutant in complex with alpha-difluoromethylornithine
Class: lyase
Keywords: polyamine metabolism, pyridoxal 5'-phosphate, alpha-beta barrel, lyase
Deposited on 1999-05-18, released 1999-11-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.212
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (ornithine decarboxylase)
    Species: Trypanosoma brucei [TaxId:5691]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2toda1, d2toda2
  • Chain 'B':
    Compound: protein (ornithine decarboxylase)
    Species: Trypanosoma brucei [TaxId:5691]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2todb1, d2todb2
  • Chain 'C':
    Compound: protein (ornithine decarboxylase)
    Species: Trypanosoma brucei [TaxId:5691]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2todc1, d2todc2
  • Chain 'D':
    Compound: protein (ornithine decarboxylase)
    Species: Trypanosoma brucei [TaxId:5691]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2todd1, d2todd2
  • Heterogens: PLP, DMO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2todA (A:)
gamdivvnddlscrflegfntrdalckkismntcdegdpffvadlgdivrkhetwkkclp
rvtpfyavacnddwrvlgtlaalgtgfdcasnteiqrvrgigvppekiiyanpckqishi
ryardsgvdvmtfdcvdelekvakthpkakmvlristddslarcrlsvkfgakvedcrfi
leqakklnidvtgvsfhvgsgstdastfaqaisdsrfvfdmgtelgfnmhildigggfpg
trdaplkfeeiagvinnalekhfppdlkltivaepgryyvasaftlavnviakkvtpgvq
tdvgahaesnaqsfmyyvndgvygsfncilydhavvrplpqrepipneklypssvwgptc
dgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyvvsglpdhvvrel
ksqks

    Sequence, based on observed residues (ATOM records): (download) 
    >2todA (A:)
gdpffvadlgdivrkhetwkkclprvtpfyavacnddwrvlgtlaalgtgfdcasnteiq
rvrgigvppekiiyanpckqishiryardsgvdvmtfdcvdelekvakthpkakmvlris
tlsvkfgakvedcrfileqakklnidvtgvsfhvgsgstdastfaqaisdsrfvfdmgte
lgfnmhildigggfpgtrdaplkfeeiagvinnalekhfppdlkltivaepgryyvasaf
tlavnviakkvtpaqsfmyyvndgvygsfncilydhavvrplpqrepipneklypssvwg
ptcdgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyvvs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2todB (B:)
gamdivvnddlscrflegfntrdalckkismntcdegdpffvadlgdivrkhetwkkclp
rvtpfyavacnddwrvlgtlaalgtgfdcasnteiqrvrgigvppekiiyanpckqishi
ryardsgvdvmtfdcvdelekvakthpkakmvlristddslarcrlsvkfgakvedcrfi
leqakklnidvtgvsfhvgsgstdastfaqaisdsrfvfdmgtelgfnmhildigggfpg
trdaplkfeeiagvinnalekhfppdlkltivaepgryyvasaftlavnviakkvtpgvq
tdvgahaesnaqsfmyyvndgvygsfncilydhavvrplpqrepipneklypssvwgptc
dgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyvvsglpdhvvrel
ksqks

    Sequence, based on observed residues (ATOM records): (download) 
    >2todB (B:)
gdpffvadlgdivrkhetwkkclprvtpfyavacnddwrvlgtlaalgtgfdcasnteiq
rvrgigvppekiiyanpckqishiryardsgvdvmtfdcvdelekvakthpkakmvlris
tlsvkfgakvedcrfileqakklnidvtgvsfhvgsgstdastfaqaisdsrfvfdmgte
lgfnmhildigggfpgtrdaplkfeeiagvinnalekhfppdlkltivaepgryyvasaf
tlavnviakkvtaqsfmyyvndgvygsfncilydhavvrplpqrepipneklypssvwgp
tcdgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyvvs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2todC (C:)
gamdivvnddlscrflegfntrdalckkismntcdegdpffvadlgdivrkhetwkkclp
rvtpfyavacnddwrvlgtlaalgtgfdcasnteiqrvrgigvppekiiyanpckqishi
ryardsgvdvmtfdcvdelekvakthpkakmvlristddslarcrlsvkfgakvedcrfi
leqakklnidvtgvsfhvgsgstdastfaqaisdsrfvfdmgtelgfnmhildigggfpg
trdaplkfeeiagvinnalekhfppdlkltivaepgryyvasaftlavnviakkvtpgvq
tdvgahaesnaqsfmyyvndgvygsfncilydhavvrplpqrepipneklypssvwgptc
dgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyvvsglpdhvvrel
ksqks

    Sequence, based on observed residues (ATOM records): (download) 
    >2todC (C:)
gdpffvadlgdivrkhetwkkclprvtpfyavacnddwrvlgtlaalgtgfdcasnteiq
rvrgigvppekiiyanpckqishiryardsgvdvmtfdcvdelekvakthpkakmvlris
tlsvkfgakvedcrfileqakklnidvtgvsfhvgsgstdastfaqaisdsrfvfdmgte
lgfnmhildigggfpgtrdaplkfeeiagvinnalekhfppdlkltivaepgryyvasaf
tlavnviakkvtpaqsfmyyvndgvygsfncilydhavvrplpqrepipneklypssvwg
ptcdgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyvvs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2todD (D:)
gamdivvnddlscrflegfntrdalckkismntcdegdpffvadlgdivrkhetwkkclp
rvtpfyavacnddwrvlgtlaalgtgfdcasnteiqrvrgigvppekiiyanpckqishi
ryardsgvdvmtfdcvdelekvakthpkakmvlristddslarcrlsvkfgakvedcrfi
leqakklnidvtgvsfhvgsgstdastfaqaisdsrfvfdmgtelgfnmhildigggfpg
trdaplkfeeiagvinnalekhfppdlkltivaepgryyvasaftlavnviakkvtpgvq
tdvgahaesnaqsfmyyvndgvygsfncilydhavvrplpqrepipneklypssvwgptc
dgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyvvsglpdhvvrel
ksqks

    Sequence, based on observed residues (ATOM records): (download) 
    >2todD (D:)
gdpffvadlgdivrkhetwkkclprvtpfyavacnddwrvlgtlaalgtgfdcasnteiq
rvrgigvppekiiyanpckqishiryardsgvdvmtfdcvdelekvakthpkakmvlris
tlsvkfgakvedcrfileqakklnidvtgvsfhvgsgstdastfaqaisdsrfvfdmgte
lgfnmhildigggfpgtrdaplkfeeiagvinnalekhfppdlkltivaepgryyvasaf
tlavnviakkvtpaqsfmyyvndgvygsfncilydhavvrplpqrepipneklypssvwg
ptcdgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyvvs