PDB entry 2r9p

View 2r9p on RCSB PDB site
Description: Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor(BPTI)
Class: hydrolase/hydrolase inhibitor
Keywords: Human mesotrypsin, Serine protease, Bovine pancreatic trypsin inhibitor, BPTI, Alternative splicing, Calcium, Digestion, Hydrolase, Metal-binding, Secreted, Sulfation, Zymogen, Pharmaceutical, Protease inhibitor, Serine protease inhibitor, hydrolase/hydrolase inhibitor COMPLEX
Deposited on 2007-09-13, released 2007-12-11
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.17
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Trypsin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: PRSS3, PRSS4, TRY3, TRY4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35030 (0-223)
      • engineered (176)
    Domains in SCOPe 2.03: d2r9pa_
  • Chain 'B':
    Compound: Trypsin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: PRSS3, PRSS4, TRY3, TRY4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35030 (0-223)
      • engineered (176)
    Domains in SCOPe 2.03: d2r9pb_
  • Chain 'C':
    Compound: Trypsin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: PRSS3, PRSS4, TRY3, TRY4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35030 (0-223)
      • engineered (176)
    Domains in SCOPe 2.03: d2r9pc_
  • Chain 'D':
    Compound: Trypsin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: PRSS3, PRSS4, TRY3, TRY4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35030 (0-223)
      • engineered (176)
    Domains in SCOPe 2.03: d2r9pd_
  • Chain 'E':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2r9pe_
  • Chain 'F':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2r9pf_
  • Chain 'G':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2r9pg_
  • Chain 'I':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2r9pi_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2r9pA (A:)
ivggytceenslpyqvslnsgshfcggsliseqwvvsaahcyktriqvrlgehnikvleg
neqfinaakiirhpkynrdtldndimliklsspavinarvstislptappaagteclisg
wgntlsfgadypdelkcldapvltqaeckasypgkitnsmfcvgfleggkdscqrdaggp
vvcngqlqgvvswghgcawknrpgvytkvynyvdwikdtiaans

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2r9pB (B:)
ivggytceenslpyqvslnsgshfcggsliseqwvvsaahcyktriqvrlgehnikvleg
neqfinaakiirhpkynrdtldndimliklsspavinarvstislptappaagteclisg
wgntlsfgadypdelkcldapvltqaeckasypgkitnsmfcvgfleggkdscqrdaggp
vvcngqlqgvvswghgcawknrpgvytkvynyvdwikdtiaans

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2r9pC (C:)
ivggytceenslpyqvslnsgshfcggsliseqwvvsaahcyktriqvrlgehnikvleg
neqfinaakiirhpkynrdtldndimliklsspavinarvstislptappaagteclisg
wgntlsfgadypdelkcldapvltqaeckasypgkitnsmfcvgfleggkdscqrdaggp
vvcngqlqgvvswghgcawknrpgvytkvynyvdwikdtiaans

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2r9pD (D:)
ivggytceenslpyqvslnsgshfcggsliseqwvvsaahcyktriqvrlgehnikvleg
neqfinaakiirhpkynrdtldndimliklsspavinarvstislptappaagteclisg
wgntlsfgadypdelkcldapvltqaeckasypgkitnsmfcvgfleggkdscqrdaggp
vvcngqlqgvvswghgcawknrpgvytkvynyvdwikdtiaans

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2r9pE (E:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2r9pF (F:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2r9pG (G:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2r9pI (I:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga