PDB entry 2r8h

View 2r8h on RCSB PDB site
Description: Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase
Class: replication, transferase/DNA
Keywords: exocyclic adducts, replication bypass, translesion, polymerase, frameshifting, REPLICATION, TRANSFERASE-DNA COMPLEX
Deposited on 2007-09-10, released 2008-07-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-12-28, with a file datestamp of 2011-12-23.
Experiment type: XRAY
Resolution: 2.48 Å
R-factor: 0.215
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase IV
    Species: Sulfolobus solfataricus [TaxId:2287]
    Gene: dbh, dpo4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2r8ha1, d2r8ha2
  • Chain 'P':
    Compound: DNA (5'-d(*dgp*dgp*dgp*dgp*dgp*dap*dap*dgp*dgp*dap*dtp*dtp*dc)-3')
  • Chain 'T':
    Compound: DNA (5'-d(*dtp*dcp*dap*dcp*(p)p*dgp*dap*dap*dtp*dcp*dcp*dtp*dtp*dcp*dcp*dcp*dcp*dc)-3')
  • Heterogens: CA, DGT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r8hA (A:)
mivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfgvkagip
iveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdkvrdyre
aynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrlireldi
advpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeynepirtr
vrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedldivsrgr
tfphgisketaysesvkllqkileederkirrigvrfskfieaigldkffdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2r8hA (A:)
mivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfgvkagip
iveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdkvrdyre
aynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrlireldi
advpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeynepirtr
vrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedldivsrgr
tfphgisketaysesvkllqkileederkirrigvrfskfi

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.