PDB entry 2r82

View 2r82 on RCSB PDB site
Description: Pyruvate phosphate dikinase (PPDK) triple mutant R219E/E271R/S262D adapts a second conformational state
Class: transferase
Keywords: phosphotransferase, conformational transition, swiveling domain, remote active sites, ATP-binding, Kinase, Magnesium, Metal-binding, Nucleotide-binding, Phosphorylation, TRANSFERASE
Deposited on 2007-09-10, released 2008-01-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-14, with a file datestamp of 2019-08-09.
Experiment type: XRAY
Resolution: 3.6 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyruvate, phosphate dikinase
    Species: Clostridium symbiosum [TaxId:1512]
    Gene: PPDK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22983
      • engineered (218)
      • engineered (261)
      • engineered (270)
    Domains in SCOPe 2.08: d2r82a1, d2r82a2, d2r82a3
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2r82A (A:)
    makwvykfeegnasmrnllggkgcnlaemtilgmpipqgftvtteacteyynsgkqitqe
    iqdqifeaitwleelngkkfgdtedpllvsvrsgarasmpgmmdtilnlglndvavegfa
    kktgnprfaydsyrrfiqmysdvvmevpkshfekiidamkeekgvhfdtdltaddlkela
    ekfkavykeamngeefpqepkdqlmgavkavfrswdnpeaivyrrmndipgdwgtavnvq
    tmvfgnkgetsgtgvaftrnpdtgekgiygrylinaqgedvvagvrtpqpitqlendmpd
    cykqfmdlamklekhfrdmqdmeftieegklyflqtrngkrtapaalqiacdlvdegmit
    eeeavvrieaksldqllhptfnpaalkagevigsalpaspgaaagkvyftadeakaahek
    gervilvrletspediegmhaaegiltvrggmtshaavvargmgtccvsgcgeikineea
    ktfelgghtfaegdyisldgstgkiykgdietqeasvsgsferimvwadkfrtlkvrtna
    dtpedtlnavklgaegiglcrtehmffeadrimkirkmilsdsveareealnelipfqkg
    dfkamykalegrpmtvryldpplhefvphteeeqaelaknmgltlaevkakvdelhefnp
    mmghrgcrlavtypeiakmqtravmeaaievkeetgidivpeimiplvgekkelkfvkdv
    vvevaeqvkkekgsdmqyhigtmieipraaltadaiaeeaeffsfgtndltqmtfgfsrd
    dagkfldsyykakiyesdpfarldqtgvgqlvemavkkgrqtrpglkcgicgehggdpss
    vefchkvglnyvscspfrvpiarlaaaqaalnnk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2r82A (A:)
    akwvykfeegnasmrnllggkgcnlaemtilgmpipqgftvtteacteyynsgkqitqei
    qdqifeaitwleelngkkfgdtedpllvsvrsgarasmpgmmdtilnlglndvavegfak
    ktgnprfaydsyrrfiqmysdvvmevpkshfekiidamkeekgvhfdtdltaddlkelae
    kfkavykeamngeefpqepkdqlmgavkavfrswdnpeaivyrrmndipgdwgtavnvqt
    mvfgnkgetsgtgvaftrnpdtgekgiygrylinaqgedvvagvrtpqpitqlendmpdc
    ykqfmdlamklekhfrdmqdmeftieegklyflqtrngkrtapaalqiacdlvdegmite
    eeavvrieaksldqllhptfnpaalkagevigsalpaspgaaagkvyftadeakaahekg
    ervilvrletspediegmhaaegiltvrggmtshaavvargmgtccvsgcgeikineeak
    tfelgghtfaegdyisldgstgkiykgdietqeasvsgsferimvwadkfrtlkvrtnad
    tpedtlnavklgaegiglcrtehmffeadrimkirkmilsdsveareealnelipfqkgd
    fkamykalegrpmtvryldpplhefvphteeeqaelaknmgltlaevkakvdelhefnpm
    mghrgcrlavtypeiakmqtravmeaaievkeetgidivpeimiplvgekkelkfvkdvv
    vevaeqvkkekgsdmqyhigtmieipraaltadaiaeeaeffsfgtndltqmtfgfsrdd
    agkfldsyykakiyesdpfarldqtgvgqlvemavkkgrqtrpglkcgicgehggdpssv
    efchkvglnyvscspfrvpiarlaaaqaalnn