PDB entry 2r64

View 2r64 on RCSB PDB site
Description: Crystal structure of a 3-aminoindazole compound with CDK2
Class: transferase
Keywords: protein kinase, inhibitor, cell division, ATP-binding, Cell cycle, Mitosis, Nucleotide-binding, Phosphorylation, Polymorphism, Serine/threonine-protein kinase, Transferase
Deposited on 2007-09-05, released 2008-09-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.221
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2r64a_
  • Heterogens: 740, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2r64A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2r64A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkivpstaireisllkelnhpnivklld
    vihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdl
    kpqnllintegaikladfglarafvtlwyrapeillgckyystavdiwslgcifaemvtr
    ralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedg
    rsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl