PDB entry 2r3q

View 2r3q on RCSB PDB site
Description: Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
Class: transferase
Keywords: SERINE/THREONINE-PROTEIN KINASE, CELL CYCLE, INHIBITION, CYCLIN-DEPENDENT KINASE, CANCER, ATP-binding, Cell division, Mitosis, Nucleotide-binding, Phosphorylation, Polymorphism, Transferase
Deposited on 2007-08-29, released 2008-01-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.35 Å
R-factor: 0.182
AEROSPACI score: 0.69 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2r3qa_
  • Heterogens: 5SC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2r3qA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2r3qA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirstaireisllkelnhpnivklldv
    ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
    pqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdiwsl
    gcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfs
    kvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl