PDB entry 2qvs

View 2qvs on RCSB PDB site
Description: Crystal Structure of Type IIa Holoenzyme of cAMP-dependent Protein Kinase
Class: transferase/transferase regulator
Keywords: crystal structure, cAMP-dependent protein kinase, Type IIa holoenzyme, isoform diversity, Alternative splicing, ATP-binding, Cytoplasm, Lipoprotein, Myristate, Nucleotide-binding, Nucleus, Phosphorylation, Serine/threonine-protein kinase, Transferase, Acetylation, cAMP-binding, transferase/transferase regulator COMPLEX
Deposited on 2007-08-08, released 2007-10-23
The last revision prior to the SCOP 1.75 freeze date was dated 2007-10-23, with a file datestamp of 2007-10-19.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.212
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: cAMP-dependent protein kinase type II-alpha regulatory subunit
    Species: MUS MUSCULUS
    Gene: Prkar2a
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: cAMP-dependent protein kinase, alpha-catalytic subunit
    Species: MUS MUSCULUS
    Gene: Prkaca, Pkaca
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2qvse1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'B':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >2qvsE (E:)
    gnaaaakkgseqesvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlv
    khkesgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvm
    eyvaggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyi
    qvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffa
    dqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfatt
    dwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef
    

    Sequence, based on observed residues (ATOM records): (download)
    >2qvsE (E:)
    esvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamk
    ildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshl
    rrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvk
    grtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivs
    gkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkvea
    pfipkfeeeirvsinekcgkeftef