PDB entry 2ql1

View 2ql1 on RCSB PDB site
Description: Structural Characterization of a Mutated, ADCC-Enhanced Human Fc Fragment
Class: immune system
Keywords: antibody, ADCC, Fc fragment, mutation, IMMUNE SYSTEM
Deposited on 2007-07-12, released 2008-04-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.53 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: IGHM protein
    Species: Homo sapiens [TaxId:9606]
    Gene: IGHM
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6PJF1
      • engineered (16)
      • engineered (107)
      • engineered (109)
    Domains in SCOPe 2.08: d2ql1a1, d2ql1a2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ql1A (A:)
thtcppcpapellggpdvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgv
evhnaktkpreeqynstyrvvsvltvlhqdwlngkeykckvsnkalplpeektiskakgq
prepqvytlppsreemtknqvsltclvkgfypsdiavewesngqpennykttppvldsdg
sfflyskltvdksrwqqgnvfscsvmhealhnhytqkslslspgk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ql1A (A:)
ggpdvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeq
ynstyrvvsvltvlhqdwlngkeykckvsnkalplpeektiskakgqprepqvytlppsr
eemtknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflyskltvdks
rwqqgnvfscsvmhealhnhytqkslsls