PDB entry 2qfw

View 2qfw on RCSB PDB site
Description: Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with isocitrate
Class: Oxidoreductase
Keywords: Rossmann fold, Oxidoreductase
Deposited on 2007-06-28, released 2008-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.235
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfwa_
  • Chain 'B':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfwb_
  • Chain 'C':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfwc_
  • Chain 'D':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfwd_
  • Chain 'E':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfwe_
  • Chain 'F':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: IDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qfwf_
  • Heterogens: ICT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qfwA (A:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfwA (A:)
skikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqdaa
eaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprlv
prwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgvam
amyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskfe
qlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpdg
ktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanile
satlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkei

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qfwB (B:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfwB (B:)
kikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqdaae
aikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprlvp
rwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgvama
myntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskfeq
lgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpdgk
tfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfaniles
atlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2qfwC (C:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfwC (C:)
skikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqdaa
eaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprlv
prwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgvam
amyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskfe
qlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpdg
ktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanile
satlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiksi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2qfwD (D:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfwD (D:)
afskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqd
aaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipripr
lvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgv
amamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqyksk
feqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtp
dgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfani
lesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiksi

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2qfwE (E:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfwE (E:)
skikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqdaa
eaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprlv
prwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgvam
amyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskfe
qlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpdg
ktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanile
satlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiks

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2qfwF (F:)
mhhhhhhamgipghafskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydls
vesrdatsdkitqdaaeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilgg
tvfrepivipriprlvprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaq
pqtlkvydykgsgvamamyntdesiegfahssfklaidkklnlflstkntilkkydgrfk
difqevyeaqykskfeqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqg
fgslglmtsilvtpdgktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrg
eldntpalckfanilesatlntvqqdgimtkdlalacgnnersayvtteefldavekrlq
keiksie

    Sequence, based on observed residues (ATOM records): (download) 
    >2qfwF (F:)
fskikvkqpvveldgdemtriiwdkikkklilpyldvdlkyydlsvesrdatsdkitqda
aeaikkygvgikcatitpdearvkefnlhkmwkspngtirnilggtvfrepivipriprl
vprwekpiiigrhahgdqykatdtlipgpgslelvykpsdpttaqpqtlkvydykgsgva
mamyntdesiegfahssfklaidkklnlflstkntilkkydgrfkdifqevyeaqykskf
eqlgihyehrliddmvaqmikskggfimalknydgdvqsdivaqgfgslglmtsilvtpd
gktfeseaahgtvtrhyrkyqkgeetstnsiasifawsrgllkrgeldntpalckfanil
esatlntvqqdgimtkdlalacgnnersayvtteefldavekrlqkeiksi