PDB entry 2qct

View 2qct on RCSB PDB site
Description: Structure of Lyp with inhibitor I-C11
Class: hydrolase
Keywords: ptpn22, lyp, ptp, hydrolase
Deposited on 2007-06-19, released 2007-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.245
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 22
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN22, PTPN8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qcta_
  • Chain 'B':
    Compound: Tyrosine-protein phosphatase non-receptor type 22
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN22, PTPN8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2qctb_
  • Heterogens: 561, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qctA (A:)
hhhhhhssglvprgshmasmdqreilqkfldeaqskkitkeefaneflklkrqstkykad
ktypttvaekpknikknrykdilpydysrvelslitsdedssyinanfikgvygpkayia
tqgplsttlldfwrmiweysvliivmacmeyemgkkkcerywaepgemqlefgpfsvsce
aekrksdyiirtlkvkfnsetrtiyqfhyknwpdhdvpssidpileliwdvrcyqeddsv
picihcsagcgrtgvicaidytwmllkdgiipenfsvfsliremrtqrpslvqtqeqyel
vynavlelfkrqm

    Sequence, based on observed residues (ATOM records): (download) 
    >2qctA (A:)
qreilqkfldefaneflklkrqstkykadktypttvaekpknikknrykdilpydysrve
lslitsdedssyinanfikgvygpkayiatqgplsttlldfwrmiweysvliivmacmey
emgkkkcerywaepgemqlefgpfsvsceaekrksdyiirtlkvkfnsetrtiyqfhykn
wpdhdvpssidpileliwdvrcyqeddsvpicihcsagcgrtgvicaidytwmllkdgii
penfsvfsliremrtqrpslvqtqeqyelvynavlelfkrqm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qctB (B:)
hhhhhhssglvprgshmasmdqreilqkfldeaqskkitkeefaneflklkrqstkykad
ktypttvaekpknikknrykdilpydysrvelslitsdedssyinanfikgvygpkayia
tqgplsttlldfwrmiweysvliivmacmeyemgkkkcerywaepgemqlefgpfsvsce
aekrksdyiirtlkvkfnsetrtiyqfhyknwpdhdvpssidpileliwdvrcyqeddsv
picihcsagcgrtgvicaidytwmllkdgiipenfsvfsliremrtqrpslvqtqeqyel
vynavlelfkrqm

    Sequence, based on observed residues (ATOM records): (download) 
    >2qctB (B:)
dqreilqkfldeaqskkeefaneflklkrqadktypttvaekpknikknrykdilpydys
rvelslitsdedssyinanfikgvygpkayiatqgplsttlldfwrmiweysvliivmac
meyemgkkkcerywaepgemqlefgpfsvsceaekrksdyiirtlkvkfnsetrtiyqfh
yknwpdhdvpssidpileliwdvrcyqeddsvpicihcsagcgrtgvicaidytwmllkd
giipenfsvfsliremrtqrpslvqtqeqyelvynavlelfkrqm