PDB entry 2qc2

View 2qc2 on RCSB PDB site
Description: Crystal structure of Severe Acute Respiratory Syndrome (SARS) 3C-like protease Asn214Ala mutant
Class: hydrolase
Keywords: hydrolase
Deposited on 2007-06-19, released 2008-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C-like proteinase
    Species: SARS coronavirus
    Gene: rep
    Database cross-references and differences (RAF-indexed):
    • Uniprot P59641 (2-End)
      • expression tag (1)
      • engineered (215)
    Domains in SCOPe 2.08: d2qc2a1, d2qc2a2
  • Chain 'B':
    Compound: 3C-like proteinase
    Species: SARS coronavirus
    Gene: rep
    Database cross-references and differences (RAF-indexed):
    • Uniprot P59641 (2-End)
      • engineered (215)
    Domains in SCOPe 2.08: d2qc2b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qc2A (A:)
gssgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedll
irksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacy
ngspsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdle
gkfygpfvdrqtaqaagtdttitlnvlawlyaaviagdrwflnrftttlndfnlvamkyn
yepltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvr
qcsgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2qc2A (A:)
ssgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedlli
rksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyn
gspsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdleg
kfygpfvdrqtaqaagtdttitlnvlawlyaaviagdrwflnrftttlndfnlvamkyny
epltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrq
csgvt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qc2B (B:)
gssgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedll
irksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacy
ngspsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdle
gkfygpfvdrqtaqaagtdttitlnvlawlyaaviagdrwflnrftttlndfnlvamkyn
yepltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvr
qcsgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2qc2B (B:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdrqtaqaagtdttitlnvlawlyaaviagdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqc
sgvtf