PDB entry 2q76

View 2q76 on RCSB PDB site
Description: Mouse anti-hen egg white lysozyme antibody F10.6.6 Fab fragment
Class: immune system
Keywords: Antibody, Fab fragment, lysozyme, affinity maturation, VH-VL interface., IMMUNE SYSTEM
Deposited on 2007-06-06, released 2008-03-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.196
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab F10.6.6 fragment Light Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Q76 (0-211)
    Domains in SCOPe 2.08: d2q76a1, d2q76a2
  • Chain 'B':
    Compound: Fab F10.6.6 fragment Heavy Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Q76 (0-215)
    Domains in SCOPe 2.08: d2q76b_
  • Chain 'C':
    Compound: Fab F10.6.6 fragment Light Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Q76 (0-211)
    Domains in SCOPe 2.08: d2q76c1, d2q76c2
  • Chain 'D':
    Compound: Fab F10.6.6 fragment Heavy Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Q76 (0-215)
    Domains in SCOPe 2.08: d2q76d_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2q76A (A:)
dieltqspatlsvtpgdsvslscrasqsisnnlhwyqqkshesprllikytsqsmsgips
rfsgsgsgtdftlsinsvetedfgvyfcqqsgswprtfgggtkldikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2q76B (B:)
evqleqsgaelmkpgasvkisckatgytfttywiewikqrpghslewigeilpgsdstyy
nekvkgkvtftadassntaymqlssltsedsavyycargdgfyvywgqgttltvssastt
ppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytl
sssvtvpsspwpsetvtcnvahpasstkvdkkivpr

    Sequence, based on observed residues (ATOM records): (download) 
    >2q76B (B:)
evqleqsgaelmkpgasvkisckatgytfttywiewikqrpghslewigeilpgsdstyy
nekvkgkvtftadassntaymqlssltsedsavyycargdgfyvywgqgttltvssastt
ppsvyplapgqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsss
vtvpsspwpsetvtcnvahpasstkvdkkivpr

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2q76C (C:)
dieltqspatlsvtpgdsvslscrasqsisnnlhwyqqkshesprllikytsqsmsgips
rfsgsgsgtdftlsinsvetedfgvyfcqqsgswprtfgggtkldikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2q76D (D:)
evqleqsgaelmkpgasvkisckatgytfttywiewikqrpghslewigeilpgsdstyy
nekvkgkvtftadassntaymqlssltsedsavyycargdgfyvywgqgttltvssastt
ppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytl
sssvtvpsspwpsetvtcnvahpasstkvdkkivpr

    Sequence, based on observed residues (ATOM records): (download) 
    >2q76D (D:)
evqleqsgaelmkpgasvkisckatgytfttywiewikqrpghslewigeilpgsdstyy
nekvkgkvtftadassntaymqlssltsedsavyycargdgfyvywgqgttltvssastt
ppsvyplapgsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsssvtv
psspwpsetvtcnvahpasstkvdkkivpr