PDB entry 2q63

View 2q63 on RCSB PDB site
Description: HIV-1 PR mutant in complex with nelfinavir
Class: hydrolase
Keywords: resistance; nelfinavir, HYDROLASE
Deposited on 2007-06-04, released 2008-02-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.191
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protease retropepsin
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03367 (0-98)
      • engineered (29)
      • engineered (54)
      • engineered (89)
    Domains in SCOPe 2.07: d2q63a_
  • Chain 'B':
    Compound: protease retropepsin
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03367 (0-98)
      • engineered (29)
      • engineered (54)
      • engineered (89)
    Domains in SCOPe 2.07: d2q63b_
  • Heterogens: 1UN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2q63A (A:)
    pqitlwqrplvtikiggqlkealldtgadntvleemslpgrwkpkmiggiggfiavrqyd
    qilieicghkaigtvlvgptpvniigrnlmtqigctlnf
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2q63B (B:)
    pqitlwqrplvtikiggqlkealldtgadntvleemslpgrwkpkmiggiggfiavrqyd
    qilieicghkaigtvlvgptpvniigrnlmtqigctlnf