PDB entry 2q4g

View 2q4g on RCSB PDB site
Description: Ensemble refinement of the protein crystal structure of human ribonuclease inhibitor complexed with ribonuclease I
Class: hydrolase/hydrolase inhibitor
Keywords: Ensemble Refinement, Refinement Methodology Development, RIBONUCLEASE-INHIBITOR COMPLEX, LEUCINE-RICH REPEAT, ENZYME-INHIBITOR COMPLEX, Structural Genomics, Protein Structure Initiative, PSI, Center for Eukaryotic Structural Genomics, CESG, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on 2007-05-31, released 2007-06-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-08-10, with a file datestamp of 2011-08-05.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.161
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'W':
    Compound: ribonuclease inhibitor
    Species: Homo sapiens [TaxId:9606]
    Gene: RNH1, PRI, RNH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2q4gw_
  • Chain 'X':
    Compound: ribonuclease pancreatic
    Species: Homo sapiens [TaxId:9606]
    Gene: RNASE1, RIB1, RNS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2q4gx_
  • Chain 'Y':
    Compound: ribonuclease inhibitor
    Species: Homo sapiens [TaxId:9606]
    Gene: RNH1, PRI, RNH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2q4gy_
  • Chain 'Z':
    Compound: ribonuclease pancreatic
    Species: Homo sapiens [TaxId:9606]
    Gene: RNASE1, RIB1, RNS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2q4gz_
  • Heterogens: CIT, HOH

PDB Chain Sequences:

  • Chain 'W':
    Sequence, based on SEQRES records: (download)
    >2q4gW (W:)
    msldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalae
    lnlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhl
    sdnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnn
    dineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklg
    dvgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdeg
    arllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvre
    lcqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlve
    svrqpgclleqlvlydiywseemedrlqalekdkpslrvis
    

    Sequence, based on observed residues (ATOM records): (download)
    >2q4gW (W:)
    sldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalael
    nlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhls
    dnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnnd
    ineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklgd
    vgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdega
    rllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvrel
    cqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlves
    vrqpgclleqlvlydiywseemedrlqalekdkpslrvis
    

  • Chain 'X':
    Sequence, based on SEQRES records: (download)
    >2q4gX (X:)
    mkesrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcf
    qekvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvh
    fdasvedst
    

    Sequence, based on observed residues (ATOM records): (download)
    >2q4gX (X:)
    esrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcfqe
    kvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvhfd
    asveds
    

  • Chain 'Y':
    Sequence, based on SEQRES records: (download)
    >2q4gY (Y:)
    msldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalae
    lnlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhl
    sdnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnn
    dineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklg
    dvgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdeg
    arllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvre
    lcqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlve
    svrqpgclleqlvlydiywseemedrlqalekdkpslrvis
    

    Sequence, based on observed residues (ATOM records): (download)
    >2q4gY (Y:)
    sldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalael
    nlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhls
    dnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnnd
    ineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklgd
    vgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdega
    rllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvrel
    cqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlves
    vrqpgclleqlvlydiywseemedrlqalekdkpslrvis
    

  • Chain 'Z':
    Sequence, based on SEQRES records: (download)
    >2q4gZ (Z:)
    mkesrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcf
    qekvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvh
    fdasvedst
    

    Sequence, based on observed residues (ATOM records): (download)
    >2q4gZ (Z:)
    esrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcfqe
    kvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvhfd
    asveds