PDB entry 2pzy

View 2pzy on RCSB PDB site
Description: Structure of MK2 Complexed with Compound 76
Class: transferase
Keywords: MK2, Protein Kinase, TRANSFERASE
Deposited on 2007-05-18, released 2007-07-31
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.251
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPKAPK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2pzya_
  • Chain 'B':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPKAPK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2pzyb_
  • Chain 'C':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPKAPK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2pzyc_
  • Chain 'D':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPKAPK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2pzyd_
  • Heterogens: B18, STU

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pzyA (A:)
qqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpk
arrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafte
reaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettshnsl
ttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrir
mgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsr
vlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records): (download) 
    >2pzyA (A:)
qfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpka
rrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdraftereas
eimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevl
gpekydkscdmwslgvimyillcgyppfysnhglaispgmktrirmgqyefpnpewsevs
eevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pzyB (B:)
qqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpk
arrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafte
reaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettshnsl
ttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrir
mgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsr
vlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records): (download) 
    >2pzyB (B:)
pqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarr
evelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafterea
seimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapev
lgpekydkscdmwslgvimyillcgyppfysgmktrirmgqyefpnpewsevseevkmli
rnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlked

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2pzyC (C:)
qqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpk
arrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafte
reaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettshnsl
ttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrir
mgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsr
vlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records): (download) 
    >2pzyC (C:)
qfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpka
rrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafter
easeimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvap
evlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrirmgqyefpnpews
evseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwedv
keemtsa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2pzyD (D:)
qqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpk
arrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafte
reaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettshnsl
ttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrir
mgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsr
vlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records): (download) 
    >2pzyD (D:)
fpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkar
revelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrftereasei
mksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettcytpyyvapev
lgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrirmgqyefpnpewsev
seevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvl