PDB entry 2pzd

View 2pzd on RCSB PDB site
Description: Crystal Structure of the HtrA2/Omi PDZ Domain Bound to a Phage-Derived Ligand (WTMFWV)
Class: hydrolase
Keywords: PDZ domain, serine protease, apoptosis, mitochondria, peptide-binding module, HYDROLASE
Deposited on 2007-05-17, released 2007-08-07
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.21
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine protease HTRA2
    Species: Homo sapiens [TaxId:9606]
    Gene: HTRA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43464 (4-End)
      • linker residues (106)
      • see remark 999 (107-112)
    Domains in SCOPe 2.01: d2pzda1
  • Chain 'B':
    Compound: Serine protease HTRA2
    Species: Homo sapiens [TaxId:9606]
    Gene: HTRA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43464 (4-End)
      • linker residues (106)
      • see remark 999 (107-112)
    Domains in SCOPe 2.01: d2pzdb1
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pzdA (A:)
gshmrryigvmmltlspsilaelqlrepsfpdvqhgvlihkvilgspahraglrpgdvil
aigeqmvqnaedvyeavrtqsqlavqirrgretltlyvtpevtegggwtmfwv

    Sequence, based on observed residues (ATOM records): (download) 
    >2pzdA (A:)
rryigvmmltlspsilaelqlrepsfpdvqhgvlihkvilgspahraglrpgdvilaige
qmvqnaedvyeavrtqsqlavqirrgretltlyvtpevtgwtmfwv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pzdB (B:)
gshmrryigvmmltlspsilaelqlrepsfpdvqhgvlihkvilgspahraglrpgdvil
aigeqmvqnaedvyeavrtqsqlavqirrgretltlyvtpevtegggwtmfwv

    Sequence, based on observed residues (ATOM records): (download) 
    >2pzdB (B:)
rryigvmmltlspsilaelqlrepsfpdvqhgvlihkvilgspahraglrpgdvilaige
qmvqnaedvyeavrtqsqlavqirrgretltlyvtpevtgwtmfwv