PDB entry 2puq

View 2puq on RCSB PDB site
Description: Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor
Class: blood clotting
Keywords: active site inhibitor; substrate profile
Deposited on 2007-05-09, released 2007-05-22
The last revision prior to the SCOP 1.73 freeze date was dated 2007-05-22, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.231
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Coagulation factor VII
    Species: HOMO SAPIENS
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2puqh1
  • Chain 'I':
    Compound: chloromethyl ketone d-trp-tyr-thr-arg substrate mimicking inhibitor
  • Chain 'L':
    Compound: Coagulation factor VII
    Species: HOMO SAPIENS
    Gene: F7
    Database cross-references and differences (RAF-indexed):
  • Chain 'T':
    Compound: tissue factor
    Species: HOMO SAPIENS
    Gene: ACE
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GLC, FUC, CA, CH2, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2puqH (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

  • Chain 'I':
    No sequence available.

  • Chain 'L':
    No sequence available.

  • Chain 'T':
    No sequence available.