PDB entry 2pt9

View 2pt9 on RCSB PDB site
Description: The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine and the inhibitor cis-4-methylcyclohexylamine (4MCHA)
Class: transferase
Keywords: TRANSFERASE, SPERMIDINE SYNTHASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, INHIBITOR COMPLEX, Structural Biology of Malarial Parasites and Other Apicomplexans
Deposited on 2007-05-08, released 2008-04-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: spermidine synthase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: PF11_0301
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pt9a_
  • Chain 'B':
    Compound: spermidine synthase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: PF11_0301
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pt9b_
  • Chain 'C':
    Compound: spermidine synthase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Gene: PF11_0301
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pt9c_
  • Heterogens: S4M, 2MH, 1PG, GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pt9A (A:)
mdklisnnklklsvvllgglcslayyhlknkfhlsqfcfskkwfsefsimwpgqafslki
kkilyetkskyqnvlvfesttygkvlvldgviqltekdefayhemmthvpmtvskepknv
lvvgggdggiirelckyksvenidiceidetvievskiyfkniscgyedkrvnvfiedas
kflenvtntydviivdssdpigpaetlfnqnfyekiynalkpngycvaqceslwihvgti
knmigyakklfkkveyanisiptypcgcigilccsktdtgltkpnkkleskefadlkyyn
yenhsaafklpafllkeieni

    Sequence, based on observed residues (ATOM records): (download) 
    >2pt9A (A:)
kkwfsefsimwpgqafslkikkilyetkskyqnvlvfesttygkvlvldgviqltekdef
ayhemmthvpmtvskepknvlvvgggdggiirelckyksvenidiceidetvievskiyf
kniscgyedkrvnvfiedaskflenvtntydviivdssdpigpaetlfnqnfyekiynal
kpngycvaqceslwihvgtiknmigyakklfkkveyanisiptypcgcigilccsktdtg
ltkpnkkleskefadlkyynyenhsaafklpafllkeieni

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pt9B (B:)
mdklisnnklklsvvllgglcslayyhlknkfhlsqfcfskkwfsefsimwpgqafslki
kkilyetkskyqnvlvfesttygkvlvldgviqltekdefayhemmthvpmtvskepknv
lvvgggdggiirelckyksvenidiceidetvievskiyfkniscgyedkrvnvfiedas
kflenvtntydviivdssdpigpaetlfnqnfyekiynalkpngycvaqceslwihvgti
knmigyakklfkkveyanisiptypcgcigilccsktdtgltkpnkkleskefadlkyyn
yenhsaafklpafllkeieni

    Sequence, based on observed residues (ATOM records): (download) 
    >2pt9B (B:)
kkwfsefsimwpgqafslkikkilyetkskyqnvlvfesttygkvlvldgviqltekdef
ayhemmthvpmtvskepknvlvvgggdggiirelckyksvenidiceidetvievskiyf
kniscgyedkrvnvfiedaskflenvtntydviivdssdpigpaetlfnqnfyekiynal
kpngycvaqceslwihvgtiknmigyakklfkkveyanisiptypcgcigilccsktdtg
ltkpnkkleskefadlkyynyenhsaafklpafllkeien

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2pt9C (C:)
mdklisnnklklsvvllgglcslayyhlknkfhlsqfcfskkwfsefsimwpgqafslki
kkilyetkskyqnvlvfesttygkvlvldgviqltekdefayhemmthvpmtvskepknv
lvvgggdggiirelckyksvenidiceidetvievskiyfkniscgyedkrvnvfiedas
kflenvtntydviivdssdpigpaetlfnqnfyekiynalkpngycvaqceslwihvgti
knmigyakklfkkveyanisiptypcgcigilccsktdtgltkpnkkleskefadlkyyn
yenhsaafklpafllkeieni

    Sequence, based on observed residues (ATOM records): (download) 
    >2pt9C (C:)
kwfsefsimwpgqafslkikkilyetkskyqnvlvfesttygkvlvldgviqltekdefa
yhemmthvpmtvskepknvlvvgggdggiirelckyksvenidiceidetvievskiyfk
niscgyedkrvnvfiedaskflenvtntydviivdssdpigpaetlfnqnfyekiynalk
pngycvaqceslwihvgtiknmigyakklfkkveyanisiptypcgcigilccsktdtgl
tkpnkkleskefadlkyynyenhsaafklpafllkeieni