PDB entry 2p4s

View 2p4s on RCSB PDB site
Description: Structure of Purine Nucleoside Phosphorylase from Anopheles gambiae in complex with DADMe-ImmH
Class: transferase
Keywords: purine nucleoside phosphorylase, TRANSFERASE
Deposited on 2007-03-13, released 2008-01-15
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.177
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: purine nucleoside phosphorylase
    Species: Anopheles gambiae [TaxId:7165]
    Gene: PNP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2p4sa_
  • Chain 'B':
    Compound: purine nucleoside phosphorylase
    Species: Anopheles gambiae [TaxId:7165]
    Gene: PNP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2p4sb_
  • Chain 'C':
    Compound: purine nucleoside phosphorylase
    Species: Anopheles gambiae [TaxId:7165]
    Gene: PNP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2p4sc_
  • Heterogens: PO4, DIH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2p4sA (A:)
mgsshhhhhhssglvprgshmskfsylqngkastngvphanghhqqhqnghsngvarngg
tatdtlpvayqqkaatsgpfhmprtehvgytydtlqeiatyllertelrpkvgiicgsgl
gtlaeqltdvdsfdyetiphfpvstvaghvgrlvfgylagvpvmcmqgrfhhyegyplak
campvrvmhligcthliatnaagganpkyrvgdimlikdhinlmgfagnnplqgpnderf
gprffgmantydpklnqqakviarqigienelregvytclggpnfetvaevkmlsmlgvd
aigmstvheiitarhcgmtcfafslitnmctmsyeeeeehchdsivgvgknrektlgefv
srivkhihyeakk

    Sequence, based on observed residues (ATOM records): (download) 
    >2p4sA (A:)
ytydtlqeiatyllertelrpkvgiicgsglgtlaeqltdvdsfdyetiphfpvstvagh
vgrlvfgylagvpvmcmqgrfhhyegyplakcampvrvmhligcthliatnaagganpky
rvgdimlikdhinlmgfagnnplqgpnderfgprffgmantydpklnqqakviarqigie
nelregvytclggpnfetvaevkmlsmlgvdaigmstvheiitarhcgmtcfafslitnm
ctmsyeeeeehchdsivgvgknrektlgefvsrivkhihyea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2p4sB (B:)
mgsshhhhhhssglvprgshmskfsylqngkastngvphanghhqqhqnghsngvarngg
tatdtlpvayqqkaatsgpfhmprtehvgytydtlqeiatyllertelrpkvgiicgsgl
gtlaeqltdvdsfdyetiphfpvstvaghvgrlvfgylagvpvmcmqgrfhhyegyplak
campvrvmhligcthliatnaagganpkyrvgdimlikdhinlmgfagnnplqgpnderf
gprffgmantydpklnqqakviarqigienelregvytclggpnfetvaevkmlsmlgvd
aigmstvheiitarhcgmtcfafslitnmctmsyeeeeehchdsivgvgknrektlgefv
srivkhihyeakk

    Sequence, based on observed residues (ATOM records): (download) 
    >2p4sB (B:)
ytydtlqeiatyllertelrpkvgiicgsglgtlaeqltdvdsfdyetiphfpvstvagh
vgrlvfgylagvpvmcmqgrfhhyegyplakcampvrvmhligcthliatnaagganpky
rvgdimlikdhinlmgfagnnplqgpnderfgprffgmantydpklnqqakviarqigie
nelregvytclggpnfetvaevkmlsmlgvdaigmstvheiitarhcgmtcfafslitnm
ctmsyeeeeehchdsivgvgknrektlgefvsrivkhihyea

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2p4sC (C:)
mgsshhhhhhssglvprgshmskfsylqngkastngvphanghhqqhqnghsngvarngg
tatdtlpvayqqkaatsgpfhmprtehvgytydtlqeiatyllertelrpkvgiicgsgl
gtlaeqltdvdsfdyetiphfpvstvaghvgrlvfgylagvpvmcmqgrfhhyegyplak
campvrvmhligcthliatnaagganpkyrvgdimlikdhinlmgfagnnplqgpnderf
gprffgmantydpklnqqakviarqigienelregvytclggpnfetvaevkmlsmlgvd
aigmstvheiitarhcgmtcfafslitnmctmsyeeeeehchdsivgvgknrektlgefv
srivkhihyeakk

    Sequence, based on observed residues (ATOM records): (download) 
    >2p4sC (C:)
ytydtlqeiatyllertelrpkvgiicgsglgtlaeqltdvdsfdyetiphfpvstvagh
vgrlvfgylagvpvmcmqgrfhhyegyplakcampvrvmhligcthliatnaagganpky
rvgdimlikdhinlmgfagnnplqgpnderfgprffgmantydpklnqqakviarqigie
nelregvytclggpnfetvaevkmlsmlgvdaigmstvheiitarhcgmtcfafslitnm
ctmsyeeeeehchdsivgvgknrektlgefvsrivkhihyea