PDB entry 2p49

View 2p49 on RCSB PDB site
Description: Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.4A resolution: native mono_1 crystal form
Class: hydrolase/immune system
Keywords: camelid single-domain antibody, vhh, cab-rn05, RNAse a, paratope, yeast surface display, hydrolase-immune system complex
Deposited on 2007-03-11, released 2007-08-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.38 Å
R-factor: 0.157
AEROSPACI score: 0.73 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ribonuclease pancreatic
    Species: Bos taurus [TaxId:9913]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2p49a_
  • Chain 'B':
    Compound: antibody cab-rn05
    Species: Camelus dromedarius [TaxId:9838]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 2P49 (0-122)
    Domains in SCOPe 2.07: d2p49b_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2p49A (A:)
    ketaaakferqhmdsstsaasssnycnqmmksrnltkdrckpvntfvhesladvqavcsq
    knvackngqtncyqsystmsitdcretgsskypncaykttqankhiivacegnpyvpvhf
    dasv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2p49A (A:)
    etaaakferqhmdsstssnycnqmmksrnltkdrckpvntfvhesladvqavcsqknvac
    kngqtncyqsystmsitdcretgsskypncaykttqankhiivacegnpyvpvhfdasv
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2p49B (B:)
    gsqvqlvesggglvqaggslrlscaasgyaytyiymgwfrqapgkeregvaamdsggggt
    lyadsvkgrftisrdkgkntvylqmdslkpedtatyycaaggyelrdrtygqwgqgtqvt
    vss