PDB entry 2p20

View 2p20 on RCSB PDB site
Description: Acetyl-CoA Synthetase, R584A mutation
Class: ligase
Keywords: Adenylate-forming enzymes, Domain Alternation, Acyl-CoA ligase, LIGASE
Deposited on 2007-03-06, released 2007-05-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.22 Å
R-factor: 0.179
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-coenzyme A synthetase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: acs
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZKF6
      • engineered (583)
    Domains in SCOPe 2.07: d2p20a_
  • Chain 'B':
    Compound: Acetyl-coenzyme A synthetase
    Species: Salmonella typhimurium [TaxId:602]
    Gene: acs
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZKF6
      • engineered (583)
    Domains in SCOPe 2.07: d2p20b_
  • Heterogens: PRX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2p20A (A:)
    msqthkhaipaniadrclinpeqyetkykqsindpdtfwgeqgkildwitpyqkvkntsf
    apgnvsikwyedgtlnlaancldrhlqengdrtaiiwegddtsqskhisyrelhrdvcrf
    antlldlgikkgdvvaiympmvpeaavamlacarigavhsvifggfspeavagriidsss
    rlvitadegvragrsiplkknvddalknpnvtsvehvivlkrtgsdidwqegrdlwwrdl
    iekaspehqpeamnaedplfilytsgstgkpkgvlhttggylvyaattfkyvfdyhpgdi
    ywctadvgwvtghsyllygplacgattlmfegvpnwptparmcqvvdkhqvnilytapta
    iralmaegdkaiegtdrsslrilgsvgepinpeawewywkkigkekcpvvdtwwqtetgg
    fmitplpgaielkagsatrpffgvqpalvdneghpqegategnlvitdswpgqartlfgd
    herfeqtyfstfknmyfsgdgarrdedgyywitgrvddvlnvsghrlgtaeiesalvahp
    kiaeaavvgiphaikgqaiyayvtlnhgeepspelyaevrnwvakeigplatpdvlhwtd
    slpktrsgkimrrilrkiaagdtsnlgdtstladpgvveklleekqaiamps
    

    Sequence, based on observed residues (ATOM records): (download)
    >2p20A (A:)
    hkhaipaniadrclinpeqyetkykqsindpdtfwgeqgkildwitpyqkvkntsfapgn
    vsikwyedgtlnlaancldrhlqengdrtaiiwegddtsqskhisyrelhrdvcrfantl
    ldlgikkgdvvaiympmvpeaavamlacarigavhsvifggfspeavagriidsssrlvi
    tadegvragrsiplkknvddalknpnvtsvehvivlkrtgsdidwqegrdlwwrdlieka
    spehqpeamnaedplfilytsgstgkpkgvlhttggylvyaattfkyvfdyhpgdiywct
    advgwvtghsyllygplacgattlmfegvpnwptparmcqvvdkhqvnilytaptairal
    maegdkaiegtdrsslrilgsvgepinpeawewywkkigkekcpvvdtwwqtetggfmit
    plpgaielkagsatrpffgvqpalvdneghpqegategnlvitdswpgqartlfgdherf
    eqtyfstfknmyfsgdgarrdedgyywitgrvddvlnvsghrlgtaeiesalvahpkiae
    aavvgiphaikgqaiyayvtlnhgeepspelyaevrnwvakeigplatpdvlhwtdslpk
    trsgkimrrilrkiaagdtsndtstladpgvveklleekqa
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2p20B (B:)
    msqthkhaipaniadrclinpeqyetkykqsindpdtfwgeqgkildwitpyqkvkntsf
    apgnvsikwyedgtlnlaancldrhlqengdrtaiiwegddtsqskhisyrelhrdvcrf
    antlldlgikkgdvvaiympmvpeaavamlacarigavhsvifggfspeavagriidsss
    rlvitadegvragrsiplkknvddalknpnvtsvehvivlkrtgsdidwqegrdlwwrdl
    iekaspehqpeamnaedplfilytsgstgkpkgvlhttggylvyaattfkyvfdyhpgdi
    ywctadvgwvtghsyllygplacgattlmfegvpnwptparmcqvvdkhqvnilytapta
    iralmaegdkaiegtdrsslrilgsvgepinpeawewywkkigkekcpvvdtwwqtetgg
    fmitplpgaielkagsatrpffgvqpalvdneghpqegategnlvitdswpgqartlfgd
    herfeqtyfstfknmyfsgdgarrdedgyywitgrvddvlnvsghrlgtaeiesalvahp
    kiaeaavvgiphaikgqaiyayvtlnhgeepspelyaevrnwvakeigplatpdvlhwtd
    slpktrsgkimrrilrkiaagdtsnlgdtstladpgvveklleekqaiamps
    

    Sequence, based on observed residues (ATOM records): (download)
    >2p20B (B:)
    khaipaniadrclinpeqyetkykqsindpdtfwgeqgkildwitpyqkvkntsfapgnv
    sikwyedgtlnlaancldrhlqengdrtaiiwegddtsqskhisyrelhrdvcrfantll
    dlgikkgdvvaiympmvpeaavamlacarigavhsvifggfspeavagriidsssrlvit
    adegvragrsiplkknvddalknpnvtsvehvivlkrtgsdidwqegrdlwwrdliekas
    pehqpeamnaedplfilytsgstgkpkgvlhttggylvyaattfkyvfdyhpgdiywcta
    dvgwvtghsyllygplacgattlmfegvpnwptparmcqvvdkhqvnilytaptairalm
    aegdkaiegtdrsslrilgsvgepinpeawewywkkigkekcpvvdtwwqtetggfmitp
    lpgaielkagsatrpffgvqpalvdneghpqegategnlvitdswpgqartlfgdherfe
    qtyfstfknmyfsgdgarrdedgyywitgrvddvlnvsghrlgtaeiesalvahpkiaea
    avvgiphaikgqaiyayvtlnhgeepspelyaevrnwvakeigplatpdvlhwtdslpkt
    rsgkimrrilrkiaagdtladpgvveklleekqai