PDB entry 2oyu

View 2oyu on RCSB PDB site
Description: Indomethacin-(S)-alpha-ethyl-ethanolamide bound to Cyclooxygenase-1
Class: oxidoreductase
Keywords: COX, PGHS, indomethacin, NSAID, heme, OXIDOREDUCTASE
Deposited on 2007-02-23, released 2007-07-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'P':
    Compound: Prostaglandin G/H synthase 1
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05979
      • see remark 999 (91)
    Domains in SCOPe 2.08: d2oyup1, d2oyup2
  • Heterogens: BOG, IMS, HEM, HOH

PDB Chain Sequences:

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >2oyuP (P:)
msrqsislrfpllllllspspvfsadpgapapvnpccyypcqhqgicvrfgldryqcdct
rtgysgpnctipeiwtwlrttlrpspsfihfllthgrwlwdfvnatfirdtlmrlvltvr
snlipspptyniahdyiswesfsnvsyytrilpsvprdcptpmgtkgkkqlpdaeflsrr
fllrrkfipdpqgtnlmfaffaqhfthqffktsgkmgpgftkalghgvdlghiygdnler
qyqlrlfkdgklkyqmlngevyppsveeapvlmhyprgippqsqmavgqevfgllpglml
yatiwlrehnrvcdllkaehptwgdeqlfqtarliligetikivieeyvqqlsgyflqlk
fdpellfgaqfqyrnriamefnqlyhwhplmpdsfrvgpqdysyeqflfntsmlvdygve
alvdafsrqpagrigggrnidhhilhvavdvikesrvlrlqpfneyrkrfgmkpytsfqe
ltgekemaaeleelygdidalefypglllekchpnsifgesmiemgapfslkgllgnpic
speywkastfggevgfnlvktatlkklvclntktcpyvsfhvpdprqedrpgverpptel

    Sequence, based on observed residues (ATOM records): (download) 
    >2oyuP (P:)
pvnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrpspsfihf
llthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsnvsyytri
lpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqhfthqffk
tsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevyppsveeapv
lmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwgdeqlfqt
arliligetikivieeyvqqlsgyflqlkfdpellfgaqfqyrnriamefnqlyhwhplm
pdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhilhvavdv
ikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefypglllek
chpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatlkklvcln
tktcpyvsfhvpd