PDB entry 2oxm

View 2oxm on RCSB PDB site
Description: Crystal structure of a UNG2/modified DNA complex that represent a stabilized short-lived extrahelical state in ezymatic DNA base flipping
Class: Hydrolase/DNA
Keywords: ENZYME DNA COMPLEX, UNG2, URACIL DNA GLYCOSYLASE, Hydrolase/DNA COMPLEX
Deposited on 2007-02-20, released 2007-10-30
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.257
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: uracil-DNA glycosylase
  Species: Homo sapiens [TaxId:9606]
  Gene: UNG, DGU, UNG1, UNG15
  Database cross-references and differences (RAF-indexed):
  • Uniprot P13051 (3-222)
    • expression tag (0-2)
  Domains in SCOPe 2.03: d2oxma_
• Chain 'B':
  Compound: DNA (5'-d(*tp*gp*tp*tp*ap*tp*cp*tp*t)-3')
  Species: synthetic, synthetic
  
• Chain 'C':
  Compound: DNA (5'-d(*ap*ap*ap*gp*ap*tp*(4mf)p*ap*cp*a)-3')
  Species: synthetic, synthetic
  
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2oxmA (A:)
  meffgeswkkhlsgefgkpyfiklmgfvaeerkhytvyppphqvftwtqmcdikdvkvvi
  lgqdpyhgpnqahglcfsvqrpvppppsleniykelstdiedfvhpghgdlsgwakqgvl
  llnavltvrahqanshkergweqftdavvswlnqnsnglvfllwgsyaqkkgsaidrkrh
  hvlqtahpsplsvyrgffgcrhfsktnellqksgkkpidwkel
  

  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  No sequence available.