PDB entry 2ovr

View 2ovr on RCSB PDB site
Description: Structure of the Skp1-Fbw7-CyclinEdegN complex
Class: transcription/cell cycle
Keywords: F-box; WD40 domains; double phosphorylation, TRANSCRIPTION-CELL CYCLE COMPLEX
Deposited on 2007-02-14, released 2007-04-24
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.225
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-phase kinase-associated protein 1A
    Species: Homo sapiens [TaxId:9606]
    Gene: SKP1A, EMC19, OCP2, SKP1, TCEB1L
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2ovra1, d2ovra2
  • Chain 'B':
    Compound: F-box/WD repeat protein 7
    Species: Homo sapiens [TaxId:9606]
    Gene: FBXW7, FBW7, FBX30, SEL10
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2ovrb1, d2ovrb2
  • Chain 'C':
    Compound: cyclinE N-terminal degron
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2OVR (0-7)
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ovrA (A:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek

    Sequence, based on observed residues (ATOM records): (download) 
    >2ovrA (A:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhdd
ipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfniknd
fteeeeaqvrkenqwc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ovrB (B:)
tqvkhmmqviepqfqrdfisllpkelalyvlsflepkdllqaaqtcrywrilaednllwr
ekckeegideplhikrrkvikpgfihspwksayirqhridtnwrrgelkspkvlkghddh
vitclqfcgnrivsgsddntlkvwsavtgkclrtlvghtggvwssqmrdniiisgstdrt
lkvwnaetgecihtlyghtstvrcmhlhekrvvsgsrdatlrvwdietgqclhvlmghva
avrcvqydgrrvvsgaydfmvkvwdpetetclhtlqghtnrvyslqfdgihvvsgsldts
irvwdvetgncihtltghqsltsgmelkdnilvsgnadstvkiwdiktgqclqtlqgpnk
hqsavtclqfnknfvitssddgtvklwdlktgefirnlvtlesggsggvvwrirasntkl
vcavgsrngteetkllvldfdvdmk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ovrB (B:)
tqvkhmmqviepqfqrdfisllpkelalyvlsflepkdllqaaqtcrywrilaednllwr
ekckeegideplhikrvikpgfihspwksayirqhridtnwrrgelkspkvlkghddhvi
tclqfcgnrivsgsddntlkvwsavtgkclrtlvghtggvwssqmrdniiisgstdrtlk
vwnaetgecihtlyghtstvrcmhlhekrvvsgsrdatlrvwdietgqclhvlmghvaav
rcvqydgrrvvsgaydfmvkvwdpetetclhtlqghtnrvyslqfdgihvvsgsldtsir
vwdvetgncihtltghqsltsgmelkdnilvsgnadstvkiwdiktgqclqtlqgpnkhq
savtclqfnknfvitssddgtvklwdlktgefirnlvtlesggsggvvwrirasntklvc
avgsrngteetkllvldfdvdm

  • Chain 'C':
    No sequence available.