PDB entry 2ovr
View 2ovr on RCSB PDB site
Description: Structure of the Skp1-Fbw7-CyclinEdegN complex
Class: transcription/cell cycle
Keywords: F-box; WD40 domains; double phosphorylation, TRANSCRIPTION-CELL CYCLE COMPLEX
Deposited on
2007-02-14, released
2007-04-24
The last revision prior to the SCOPe 2.01 freeze date was dated
2011-11-16, with a file datestamp of
2011-11-11.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.225
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: S-phase kinase-associated protein 1A
Species: Homo sapiens [TaxId:9606]
Gene: SKP1A, EMC19, OCP2, SKP1, TCEB1L
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d2ovra1, d2ovra2 - Chain 'B':
Compound: F-box/WD repeat protein 7
Species: Homo sapiens [TaxId:9606]
Gene: FBXW7, FBW7, FBX30, SEL10
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d2ovrb1, d2ovrb2 - Chain 'C':
Compound: cyclinE N-terminal degron
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2ovrA (A:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek
Sequence, based on observed residues (ATOM records): (download)
>2ovrA (A:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhdd
ipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfniknd
fteeeeaqvrkenqwc
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2ovrB (B:)
tqvkhmmqviepqfqrdfisllpkelalyvlsflepkdllqaaqtcrywrilaednllwr
ekckeegideplhikrrkvikpgfihspwksayirqhridtnwrrgelkspkvlkghddh
vitclqfcgnrivsgsddntlkvwsavtgkclrtlvghtggvwssqmrdniiisgstdrt
lkvwnaetgecihtlyghtstvrcmhlhekrvvsgsrdatlrvwdietgqclhvlmghva
avrcvqydgrrvvsgaydfmvkvwdpetetclhtlqghtnrvyslqfdgihvvsgsldts
irvwdvetgncihtltghqsltsgmelkdnilvsgnadstvkiwdiktgqclqtlqgpnk
hqsavtclqfnknfvitssddgtvklwdlktgefirnlvtlesggsggvvwrirasntkl
vcavgsrngteetkllvldfdvdmk
Sequence, based on observed residues (ATOM records): (download)
>2ovrB (B:)
tqvkhmmqviepqfqrdfisllpkelalyvlsflepkdllqaaqtcrywrilaednllwr
ekckeegideplhikrvikpgfihspwksayirqhridtnwrrgelkspkvlkghddhvi
tclqfcgnrivsgsddntlkvwsavtgkclrtlvghtggvwssqmrdniiisgstdrtlk
vwnaetgecihtlyghtstvrcmhlhekrvvsgsrdatlrvwdietgqclhvlmghvaav
rcvqydgrrvvsgaydfmvkvwdpetetclhtlqghtnrvyslqfdgihvvsgsldtsir
vwdvetgncihtltghqsltsgmelkdnilvsgnadstvkiwdiktgqclqtlqgpnkhq
savtclqfnknfvitssddgtvklwdlktgefirnlvtlesggsggvvwrirasntklvc
avgsrngteetkllvldfdvdm
- Chain 'C':
No sequence available.