PDB entry 2ovq
View 2ovq on RCSB PDB site
Description: Structure of the Skp1-Fbw7-CyclinEdegC complex
Class: transcription/cell cycle
Keywords: F-box; WD40 domains; double phosphorylation, TRANSCRIPTION-CELL CYCLE COMPLEX
Deposited on
2007-02-14, released
2007-04-24
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-18, with a file datestamp of
2017-10-13.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.18
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: S-phase kinase-associated protein 1A
Species: Homo sapiens [TaxId:9606]
Gene: SKP1A, EMC19, OCP2, SKP1, TCEB1L
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2ovqa1, d2ovqa2 - Chain 'B':
Compound: F-box/WD repeat protein 7
Species: Homo sapiens [TaxId:9606]
Gene: FBXW7, FBW7, FBX30, SEL10
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2ovqb1, d2ovqb2 - Chain 'C':
Compound: cyclinE C-terminal degron
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2ovqA (A:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek
Sequence, based on observed residues (ATOM records): (download)
>2ovqA (A:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhdi
pvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfnikndf
teeeeaqvrkenqw
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2ovqB (B:)
tqvkhmmqviepqfqrdfisllpkelalyvlsflepkdllqaaqtcrywrilaednllwr
ekckeegideplhikrrkvikpgfihspwksayirqhridtnwrrgelkspkvlkghddh
vitclqfcgnrivsgsddntlkvwsavtgkclrtlvghtggvwssqmrdniiisgstdrt
lkvwnaetgecihtlyghtstvrcmhlhekrvvsgsrdatlrvwdietgqclhvlmghva
avrcvqydgrrvvsgaydfmvkvwdpetetclhtlqghtnrvyslqfdgihvvsgsldts
irvwdvetgncihtltghqsltsgmelkdnilvsgnadstvkiwdiktgqclqtlqgpnk
hqsavtclqfnknfvitssddgtvklwdlktgefirnlvtlesggsggvvwrirasntkl
vcavgsrngteetkllvldfdvdmk
Sequence, based on observed residues (ATOM records): (download)
>2ovqB (B:)
tqvkhmmqviepqfqrdfisllpkelalyvlsflepkdllqaaqtcrywrilaednllwr
ekckeegideplhikrrkvikpgfihspwksayirqhridtnwrrgelkspkvlkghddh
vitclqfcgnrivsgsddntlkvwsavtgkclrtlvghtggvwssqmrdniiisgstdrt
lkvwnaetgecihtlyghtstvrcmhlhekrvvsgsrdatlrvwdietgqclhvlmghva
avrcvqydgrrvvsgaydfmvkvwdpetetclhtlqghtnrvyslqfdgihvvsgsldts
irvwdvetgncihtltghqsltsgmelkdnilvsgnadstvkiwdiktgqclqtlqgpnk
hqsavtclqfnknfvitssddgtvklwdlktgefirnlvtlesggsggvvwrirasntkl
vcavgsrngteetkllvldfdvdm
- Chain 'C':
No sequence available.