PDB entry 2opr
View 2opr on RCSB PDB site
Description: Crystal Structure of K101E Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.
Class: transferase
Keywords: hiv-1 reverse transcriptase, aids, nnrti, gw420867x, drug resistance, transferase
Deposited on
2007-01-30, released
2007-05-22
The last revision prior to the SCOPe 2.02 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.232
AEROSPACI score: 0.2
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Reverse transcriptase/ribonuclease H
Species: HIV-1 M:B_HXB2R [TaxId:11706]
Gene: gag-pol
Database cross-references and differences (RAF-indexed):
- Uniprot P04585 (0-546)
- engineered (99)
- modified residue (278)
- Chain 'B':
Compound: p51 RT
Species: HIV-1 M:B_HXB2R [TaxId:11706]
Gene: gag-pol
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d2oprb_ - Heterogens: HBQ
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2oprB (B:)
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwevqlgiphpaglekkksvtvldvgdayfsvpldedfr
kytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymd
dlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpiv
lpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelae
nreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndv
kqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvkl
wyqlek
Sequence, based on observed residues (ATOM records): (download)
>2oprB (B:)
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfiphpaglekkksvtvldvgdayfsvpldedfrkytaft
ipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgs
dleigqhrtkieelrqhllrwelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiy
pgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqk
qgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfkl
piqketwetwwteywqatwipewefvntpplvklwyqlek