PDB entry 2oic

View 2oic on RCSB PDB site
Description: Crystal structure of IRAK4 kinase domain complexed with staurosporine
Class: Transferase
Keywords: kinase, Transferase
Deposited on 2007-01-10, released 2007-03-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.226
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NWZ3
      • modified residue (182)
      • modified residue (185-186)
  • Chain 'B':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NWZ3
      • modified residue (185-186)
  • Chain 'C':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NWZ3
      • modified residue (182)
      • modified residue (185-186)
    Domains in SCOPe 2.06: d2oicc_
  • Chain 'D':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NWZ3
      • modified residue (182)
      • modified residue (185-186)
    Domains in SCOPe 2.06: d2oicd_
  • Heterogens: STU, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2oicC (C:)
vsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamv
ditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldg
tpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekf
aqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldi
keeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta
s

    Sequence, based on observed residues (ATOM records): (download) 
    >2oicC (C:)
sdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkkleelkq
qfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmr
ckiaqgaanginflhenhhihrdiksanilldeaftakisdfgtvmtsrivgttaymape
alrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkkm
ndadstsveamysvasqclhekknkrpdikkvqqllqemt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2oicD (D:)
vsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamv
ditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldg
tpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekf
aqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldi
keeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta
s

    Sequence, based on observed residues (ATOM records): (download) 
    >2oicD (D:)
sdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkkllkqqf
dqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrck
iaqgaanginflhenhhihrdiksanilldeaftakisdfglaraseaqtvmtsrivgtt
aymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektied
yidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta