PDB entry 2o0o

View 2o0o on RCSB PDB site
Description: Crystal structure of TL1A
Class: cytokine, hormone/growth factor
Keywords: VEGI, homotrimer, metal binding, cancer, angiogenesis, inflammation, CYTOKINE, HORMONE-GROWTH FACTOR COMPLEX
Deposited on 2006-11-27, released 2007-10-30
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.243
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TNF superfamily ligand TL1A
    Species: Homo sapiens [TaxId:9606]
    Gene: TNFSF15
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2o0oa_
  • Chain 'B':
    Compound: TNF superfamily ligand TL1A
    Species: Homo sapiens [TaxId:9606]
    Gene: TNFSF15
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2o0ob_
  • Chain 'C':
    Compound: TNF superfamily ligand TL1A
    Species: Homo sapiens [TaxId:9606]
    Gene: TNFSF15
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2o0oc_
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2o0oA (A:)
    lkgqefapshqqvyaplradgdkprahltvvrqtptqhfknqfpalhwehelglaftknr
    mnytnkfllipesgdyfiysqvtfrgmtsecseirqagrpnkpdsitvvitkvtdsypep
    tqllmgtksvcevgsnwfqpiylgamfslqegdklmvnvsdislvdytkedktffgafll
    

    Sequence, based on observed residues (ATOM records): (download)
    >2o0oA (A:)
    gdkprahltvvrqtptqhfknqfpalhwehelglaftknrmnytnkfllipesgdyfiys
    qvtfrgmtsecrpnkpdsitvvitkvtdsypeptqllmgtksvcevgsnwfqpiylgamf
    slqegdklmvnvsdislvdytkedktffgafll
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2o0oB (B:)
    lkgqefapshqqvyaplradgdkprahltvvrqtptqhfknqfpalhwehelglaftknr
    mnytnkfllipesgdyfiysqvtfrgmtsecseirqagrpnkpdsitvvitkvtdsypep
    tqllmgtksvcevgsnwfqpiylgamfslqegdklmvnvsdislvdytkedktffgafll
    

    Sequence, based on observed residues (ATOM records): (download)
    >2o0oB (B:)
    gdkprahltvvrqtptqhfknqfpalhwehelglaftknrmnytnkfllipesgdyfiys
    qvtfrgmtsecrpnkpdsitvvitkvtdsypeptqllmgtksvcevgsnwfqpiylgamf
    slqegdklmvnvsdislvdytkedktffgafll
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2o0oC (C:)
    lkgqefapshqqvyaplradgdkprahltvvrqtptqhfknqfpalhwehelglaftknr
    mnytnkfllipesgdyfiysqvtfrgmtsecseirqagrpnkpdsitvvitkvtdsypep
    tqllmgtksvcevgsnwfqpiylgamfslqegdklmvnvsdislvdytkedktffgafll
    

    Sequence, based on observed residues (ATOM records): (download)
    >2o0oC (C:)
    gdkprahltvvrqtptqhfknqfpalhwehelglaftknrmnytnkfllipesgdyfiys
    qvtfrgmtsecpnkpdsitvvitkvtdsypeptqllmgtksvcevgsnwfqpiylgamfs
    lqegdklmvnvsdislvdytkedktffgafll