PDB entry 2o0o
View 2o0o on RCSB PDB site
Description: Crystal structure of TL1A
Class: cytokine, hormone/growth factor
Keywords: VEGI, homotrimer, metal binding, cancer, angiogenesis, inflammation, CYTOKINE, HORMONE-GROWTH FACTOR COMPLEX
Deposited on
2006-11-27, released
2007-10-30
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.243
AEROSPACI score: 0.17
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: TNF superfamily ligand TL1A
Species: Homo sapiens [TaxId:9606]
Gene: TNFSF15
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2o0oa_ - Chain 'B':
Compound: TNF superfamily ligand TL1A
Species: Homo sapiens [TaxId:9606]
Gene: TNFSF15
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2o0ob_ - Chain 'C':
Compound: TNF superfamily ligand TL1A
Species: Homo sapiens [TaxId:9606]
Gene: TNFSF15
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2o0oc_ - Heterogens: MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2o0oA (A:)
lkgqefapshqqvyaplradgdkprahltvvrqtptqhfknqfpalhwehelglaftknr
mnytnkfllipesgdyfiysqvtfrgmtsecseirqagrpnkpdsitvvitkvtdsypep
tqllmgtksvcevgsnwfqpiylgamfslqegdklmvnvsdislvdytkedktffgafll
Sequence, based on observed residues (ATOM records): (download)
>2o0oA (A:)
gdkprahltvvrqtptqhfknqfpalhwehelglaftknrmnytnkfllipesgdyfiys
qvtfrgmtsecrpnkpdsitvvitkvtdsypeptqllmgtksvcevgsnwfqpiylgamf
slqegdklmvnvsdislvdytkedktffgafll
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2o0oB (B:)
lkgqefapshqqvyaplradgdkprahltvvrqtptqhfknqfpalhwehelglaftknr
mnytnkfllipesgdyfiysqvtfrgmtsecseirqagrpnkpdsitvvitkvtdsypep
tqllmgtksvcevgsnwfqpiylgamfslqegdklmvnvsdislvdytkedktffgafll
Sequence, based on observed residues (ATOM records): (download)
>2o0oB (B:)
gdkprahltvvrqtptqhfknqfpalhwehelglaftknrmnytnkfllipesgdyfiys
qvtfrgmtsecrpnkpdsitvvitkvtdsypeptqllmgtksvcevgsnwfqpiylgamf
slqegdklmvnvsdislvdytkedktffgafll
- Chain 'C':
Sequence, based on SEQRES records: (download)
>2o0oC (C:)
lkgqefapshqqvyaplradgdkprahltvvrqtptqhfknqfpalhwehelglaftknr
mnytnkfllipesgdyfiysqvtfrgmtsecseirqagrpnkpdsitvvitkvtdsypep
tqllmgtksvcevgsnwfqpiylgamfslqegdklmvnvsdislvdytkedktffgafll
Sequence, based on observed residues (ATOM records): (download)
>2o0oC (C:)
gdkprahltvvrqtptqhfknqfpalhwehelglaftknrmnytnkfllipesgdyfiys
qvtfrgmtsecpnkpdsitvvitkvtdsypeptqllmgtksvcevgsnwfqpiylgamfs
lqegdklmvnvsdislvdytkedktffgafll