PDB entry 2nzg

View 2nzg on RCSB PDB site
Description: Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin, 1.9A crystal structure reveals the details
Class: toxin
Keywords: Protein-carbohydrate complex, cholera toxin, heat-labile enterotoxin, blood group antigen
Deposited on 2006-11-23, released 2007-02-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2008-09-23, with a file datestamp of 2008-09-19.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.186
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'D':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
    Domains in SCOPe 2.07: d2nzgd_
  • Chain 'E':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
    Domains in SCOPe 2.07: d2nzge_
  • Chain 'F':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
    Domains in SCOPe 2.07: d2nzgf_
  • Chain 'G':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
    Domains in SCOPe 2.07: d2nzgg_
  • Chain 'H':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
    Domains in SCOPe 2.07: d2nzgh_
  • Chain 'I':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
    Domains in SCOPe 2.07: d2nzgi_
  • Chain 'J':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
  • Chain 'K':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
    Domains in SCOPe 2.07: d2nzgk_
  • Chain 'L':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
    Domains in SCOPe 2.07: d2nzgl_
  • Chain 'M':
    Compound: Cholera enterotoxin subunit B
    Species: Vibrio cholerae [TaxId:666]
    Domains in SCOPe 2.07: d2nzgm_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2nzgD (D:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >2nzgD (D:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgqkkaie
rmkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2nzgE (E:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >2nzgE (E:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpsqkkaie
rmkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2nzgF (F:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >2nzgF (F:)
apqnitelcseyhntqiytindkilsyteslrgkemaiitfkngatfqvevdsqkkaier
mkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2nzgG (G:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >2nzgG (G:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpqkkaier
mkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2nzgH (H:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >2nzgH (H:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpghidsqk
kaiermkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2nzgI (I:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >2nzgI (I:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpqkkaier
mkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2nzgK (K:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >2nzgK (K:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvekkaiermkd
tlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2nzgL (L:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >2nzgL (L:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpdsqkkai
ermkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >2nzgM (M:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >2nzgM (M:)
apqnitelcseyhntqiytindkilsyteslrgkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisma