PDB entry 2nz8

View 2nz8 on RCSB PDB site
Description: N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1
Class: signaling protein,cell cycle
Keywords: Trio; Rac1; Dbl-family GEF; Rho-family GTPase; DH/PH cassette, SIGNALING PROTEIN,CELL CYCLE
Deposited on 2006-11-22, released 2007-04-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-19.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.225
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ras-related C3 botulinum toxin substrate 1 isoform Rac1
    Species: Homo sapiens [TaxId:9606]
    Gene: RAC1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2nz8a_
  • Chain 'B':
    Compound: triple functional domain protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TRIO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2nz8b1, d2nz8b2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2nz8A (A:)
mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2nz8B (B:)
gamekrksarrkefimaeliqtekayvrdlrecmdtylwemtsgveeippgivnkeliif
gnmqeiyefhnniflkelekyeqlpedvghcfvtwadkfqmyvtycknkpdstqlileha
gsyfdeiqqrhglansissylikpvqritkyqlllkelltcceegkgeikdglevmlsvp
krandamhlsmlegfdeniesqgelilqesfqvwdpktlirkgrerhlflfemslvfske
vkdssgrskylyksklftselgvtehvegdpckfalwvgrtptsdnkivlkassienkqd
wikhireviqert

    Sequence, based on observed residues (ATOM records): (download) 
    >2nz8B (B:)
arrkefimaeliqtekayvrdlrecmdtylwemtsgveeippgivnkeliifgnmqeiye
fhnniflkelekyeqlpedvghcfvtwadkfqmyvtycknkpdstqlilehagsyfdeiq
qrhglansissylikpvqritkyqlllkelltcceegkgeikdglevmlsvpkrandamh
lsmlegfsqgelilqesfqhlflfemslvfskevkdssgrskylyksklftselgvtehv
egdpckfatsdnkivlkassienkqdwikhireviqert