PDB entry 2nxy

View 2nxy on RCSB PDB site
Description: HIV-1 gp120 Envelope Glycoprotein(S334A) Complexed with CD4 and Antibody 17b
Class: viral protein/immune system
Keywords: HIV, gp120, antibody, CD4
Deposited on 2006-11-20, released 2007-02-06
The last revision prior to the SCOP 1.73 freeze date was dated 2007-02-27, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.183
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: envelope glycoprotein gp120
    Species: Human immunodeficiency virus 1
  • Chain 'B':
    Compound: T-cell surface glycoprotein cd4
    Species: HOMO SAPIENS
    Gene: CD4
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2nxyb1, d2nxyb2
  • Chain 'C':
    Compound: antibody 17b, light chain
    Species: HOMO SAPIENS
    Domains in SCOP 1.73: d2nxyc1, d2nxyc2
  • Chain 'D':
    Compound: antibody 17b, heavy chain
    Species: HOMO SAPIENS
    Domains in SCOP 1.73: d2nxyd1, d2nxyd2
  • Heterogens: NAG, HEZ, TRS, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2nxyB (B:)
mkkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrr
slwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltle
sppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvlaf
qkas

    Sequence, based on observed residues (ATOM records): (download) 
    >2nxyB (B:)
kkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrrs
lwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltles
ppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvlafq
k

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2nxyC (C:)
divmtqspatlsvspgeratlscrasesvssdlawyqqkpgqaprlliygastratgvpa
rfsgsgsgaeftltisslqsedfavyycqqynnwpprytfgqgtrleikrtvaapsvfif
ppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
ltlskadyekhkvyacevthqglsspvtksfnrg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2nxyD (D:)
evqlvesgaevkkpgssvkvsckasgdtfirysftwvrqapgqglewmgriitildvahy
aphlqgrvtitadkststvylelrnlrsddtavyfcagvyegeadegeydnngflkhwgq
gtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvht
fpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

    Sequence, based on observed residues (ATOM records): (download) 
    >2nxyD (D:)
evqlvesgaevkkpgssvkvsckasgdtfirysftwvrqapgqglewmgriitildvahy
aphlqgrvtitadkststvylelrnlrsddtavyfcagvyegeadegeydnngflkhwgq
gtlvtvssastkgpsvfplapsstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk